Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-000048
Title: Evaluation of wound healing activity of Calotropain – P
Category: Pharmaceutical Chemistry
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    In the present study the isolated compound ‘Calotropain – P’ was employed for its wound healing activity. For the assessment of wound healing activity, Swiss Wister stain rats were employed and the various parameters such as excision wounds, incision wounds and dead space wounds were studied. In excision wound model, treatment was continued till the complete healing of the wound, in incision and dead space wound model the treatment was continued for 10 days. For topical application, 5% w/w ointment of ‘Calotropain-P’ was prepared in 2% sodium alginate and in excision and incision wound models. The healing of the wound was assessed by the rate of wound contraction, period of epithelialisation, skin breaking strength, granulation strength and histopathology of the granulation tissue. It was found that the isolated compound Calotropain-P’ possesses significant wound healing activity.

  • Abstract Audio

    Click Here

  • About the authors and Affiliations

    Author(s) Name:

    Kar Subrat *a, Basu S.K. b, Dutta S.Ka, Negi Samikshyaa.

    Affiliation(s) Name:

    aDepartment of Pharmachemistry, Seemanta Institute of Pharmaceutical Sciences, Jharpokharia-757086, Orissa, India.
    bDepartment of Pharmaceutical Technology, Jadavpur University, Kolkata-757032, India

    For correspondence: Kar Subrat, aDepartment of Pharmachemistry, Seemanta Institute of Pharmaceutical Sciences, Jharpokharia-757086, Orissa, India.

    E-mail: subrat_sips@yahoo.com,eskabee@yahoo.com
    Received on: 08-05-2008; Accepted on :22-09-2008

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Kar Subrat *a, Basu S.K. b, Dutta S.Ka, Negi Samikshyaa.

    Title:Evaluation of wound healing activity of Calotropain – P
    Journal:Journal of Pharmacy Research
    Vol(issue):1(2)
    Year:2008
    Page No: (276-279)
  • Experimental Methods Keywords

    Methodology:Wound Healing Activity, Excision wound, Incision wound
    Research Materials:Calotropain-P

Keywords

Wound healing activity Calotropain-P.

Our Services

Most Downloaded List