Journal: Drug Invention Today

Article Id: JPRS-P'Col-00004869
Title: Abnormalities of liver function tests in a patient with tuberculosis on antituberculous treatment
Category: Pharmacology
Section: Research Article
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    Background: Tuberculosis (TB) remains a noteworthy worldwide medical issue even though the causative living being was found over 120 years prior and profoundly compelling medications and antibody are accessible making TB a preventable and treatable malady. India is the most astounding TB load nation on the planet. It represents almost one-fifth of the worldwide weight of TB. Consistently, all-inclusive around 18 lakh people create TB, of which around 8 lakh are new smear constructive very irresistible cases and about 4.17 lakh individuals pass on of TB; consistently, two people kick the bucket each 3 min and around 1000 individuals pass on consistently. Methodology: Patients liver function will be assessed by measuring serum bilirubin, serum alkaline phosphatase (SAP), serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), serum proteins, and prothrombin time. Results: Out of 50 patients on anti-TB treatment, four patients had increased serum bilirubin, SGOT, and SGPT. All these four patients are chronic alcoholic. Conclusion: The management of drug-induced liver disease and active TB in these patients is difficult and the hepatotoxicity of anti-TB drugs is enhanced in transplant patients.

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    Author(s) Name:

    B. Muthukumarasamy*, Ranjith

    Affiliation(s) Name:

    Department of General Medicine, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India (Bharath Instit of Higher Education and Research, Chennai, Tamil Nadu, India)

    *Corresponding author: Dr. B. Muthukumarasamy, Department of General Medicine, Sri Lakshmi Narayana Institu Medical Sciences, Pondicherry, India (Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India)

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    Author:

    B. Muthukumarasamy*, Ranjith

    Title:Abnormalities of liver function tests in a patient with tuberculosis on antituberculous treatment
    Journal:Drug Invention Today
    Vol(issue):12 (December )
    Year:2019
    Page No: (3038-3040)
  • Experimental Methods Keywords

    Methodology: Liver dysfunction, Pathogenesis, Tuberculosis
    Research Materials:patient with tuberculosis

Keywords

Liver dysfunction Pathogenesis Tuberculosis

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