Journal: Journal of Pharmacy Research

Article Id: JPRS-ORS-000050
Title: Changes in the structural protein concentrations of neurones and glia cells in some centre of the hypothalamus at different periods of starvation and dehydration
Category: Others ( Related Science )
Section: Research Article
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    This study was carried out to determine alterations in the structural protein concentrations of the neurones and glia cells in different centre of the hypothalamus. Hundred Wistar Albino rats were left for starvation and dehydration. And then, for the restoration of starvation and dehydration the rats were fed and given water ad libitum. The concentration of the structural proteins was determined under the interference microscope. Results showed that the concentration of the structural proteins increased significantly (P<0, 01) in the cytoplasm of the neurones in the lateral centre of the hypothalamus, at 3rd day of starvation. However, it decreased significantly (P<0,001) at 5th day of starvation. The concentrations of the structural proteins in the cytoplasm of the glia cells also increased significantly at 5th day of starvation. The structural protein concentrations in nuclei and cytoplasm of the neurones and glia cells in all the examined centres decreased significantly (P<0, 01) especially in neurones. As a result, it might be postulated that there is a mechanism responsible for the regulation of food water intake in case of metabolic deficiency.

    Cite this article as : Atilla TEMUR, Fahrettin ASKEROV, Hüseyin KARADAÐ, Changes in the structural protein concentrations of neurones and glia cells in some centre of the hypothalamus at different periods of starvation and dehydration,Journal of Pharmacy Research, Vol.2.Issue 1. January 2009,14-17.

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    Author(s) Name:

    *Atilla TEMUR1, Fahrettin ASKEROV2 , Hüseyin KARADAÐ3

    Affiliation(s) Name:

    1 Yüzüncü Yýl University, Faculty of Education, 65080 Van-TÜRKÝYE
    2 Azerbaijan n.a.A.I. Karayev Institute of Physiology, Baku- AZERBAIJAN
    3Yüzüncü Yýl Üniversity, Veterinary Faculty, Van – TÜKÝYE

     

    For correspondence:

    Atilla TEMUR,

    Yüzüncü Yýl University, Faculty of Education, 65080 Van-TÜRKÝYE


    E-mail: atillatemur@hotmail.com

    Received on:12-08-2008; Accepted on 16-10-2008

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    Author:

    *Atilla TEMUR1, Fahrettin ASKEROV2 , Hüseyin KARADAÐ3

    Title:Changes in the structural protein concentrations of neurones and glia cells in some centre of the hypothalamus at different periods of starvation and dehydration
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (January )
    Year:2009
    Page No: (13-17)
  • Experimental Methods Keywords

    Methodology:Changes in the structural protein concentrations
    Research Materials:neurones and glia cells

Keywords

Starvation dehydration hypothalamus structural protein

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