Journal: Drug Invention Today

Article Id: JPRS-DFA-00005035
Title: The gas chromatography–mass spectrometry study of one herbal formulation, Trikatu Churnam
Category: Drug or Formulation Analysis
Section: Research Article
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    Objective: The present study deals with the gas chromatography–mass spectrometry (GC– MS) analysis of one digestive Ayurvedic formulation, Induppukanam. Materials and Methods: Induppukanam was procured form a standard Ayurvedic vendor at Chennai and was subjected to GC–MS analysis following standard procedure. Results: Some important molecules such as thymol, Methyl-4,7,10,13-hexadecatetraenoate, Chloroacetic acid, pentadecyl ester, Methyl-4,7,10,13-hexadecatetraenoate, Santalol, E-cis,epi-.beta.-, n-Hexadecanoic acid, 4-Vinylbenzoic acid, 2-Phenyl-3-methoxy-cyclopropane-1-carboxylic acid, Ricinoleic acid, 5-Methyl-5-triazolo(1,5-a)pyrimidine etc. have mostly actions related to hormonal balance. The role of some molecules such as 1,2,3-Benzenetriol, (4R,5S)-4-Hydroxymethyl-5-hydroxytricyclo[4.4.0.0(3,8)]decane, Nonane, 2,2,4,4,6,8,8-heptamethyl-, (R)-(-)-14-Methyl-8-hexadecyn-1-ol, 9-Octadecenoic acid, (E)- and 2H-Pyrazino[1,2-b] isoquinoline-1,3(4H,6H)-dione, and 2-(4-fluorophenyl)-11,11a-dihydro-8,9-dimethoxy- are known. Conclusion: The direct evidence of Induppukanam as digestive formulation is not reflected by the molecules, whose roles are known. It will be of interest to work on those molecules whose medicinal roles are not reported yet, which could lead to a better understanding of the mechanism of action of Induppukanam.

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    Author(s) Name:

    M. Kotteswari 1 , K. Prabhu1 , Mudiganti Ram Krishna Rao2 *, G. Charishma2 , T. K. Balaji 3 , Shruti Dinakar4 , R. Lakshmi Sundaram5

    Affiliation(s) Name:

    1 Department of Anatomy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India,

    2 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India,

    3 Department of Anatomy, Chettinad Academy of Research and Education, Chennai, Tamil Nadu, India,

    4 Ayurvedic Practitioner, Kottakkal Arya Vaidya Sala, Chennai, Tamil Nadu, India,

    5 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India

    *Corresponding author: Mudiganti Ram Krishna Rao, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India

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    Author:

    M. Kotteswari 1 , K. Prabhu1 , Mudiganti Ram Krishna Rao2 *, G. Charishma2 , T. K. Balaji 3 , Shruti Dinakar4 , R. Lakshmi Sundaram5

    Title:The gas chromatography–mass spectrometry study of one herbal formulation, Trikatu Churnam
    Journal:Drug Invention Today
    Vol(issue):14 (May)
    Year:2020
    Page No: (740-752)
  • Experimental Methods Keywords

    Methodology:gas chromatography–mass spectrometry study
    Research Materials:herbal formulation, Trikatu Churnam

Keywords

Alpha-ylangene Ayurvedic Beta-bisabolene Caryophyllene oxide Digestive Dodecanedioic acid Longipinocarveol Trans- Trikatu Churnam

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