Journal: Drug Invention Today

Article Id: JPRS-DFA-00005045
Title: Gas chromatography–mass spectrometry study of one Ayurvedic Rasayana drug, Dhanwantari Rasayanam
Category: Drug or Formulation Analysis
Section: Research Article
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    Objective: The present study deals with the gas chromatography–mass spectrometry (GC–MS) analysis of one famous nerve stimulating tonic, Dhanwantari Rasayanam. This knowledge of the molecules present in this medicine could indicate the mechanism of action of this medicine, which is basically used to treat nerve-related disease such as paraplegia, hemiplegia, and muscle wasting. Materials and Methods: Dhanwantari Rasayanam was brought from standard Ayurvedic vendor from Chennai. The GC–MS analysis was conducted following standard procedures. Results: It was observed that there are some important biomolecules such as heptanediamide, N,N’-di-benzoyloxy-, 5-Hydroxymethylfurfural.,beta.-Asarone, Tetradecanoic acid, 15-Hydroxypentadecanoic acid, oleic acid, hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, and 26-Nor-5-cholesten-3.beta.-ol-25-one show some interesting biological activities which are in tune with the medicinal roles of Dhanwantari Rasayanam. Conclusion: The results indicate a positive correlation between the medicinal roles of molecules present in GC–MS profile and that of the Rasayanam itself.

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    Author(s) Name:

    K. Prabhu1 , Mudiganti Ram Krishna Rao2 *, S. K. Vishal 2 , A. K. Bharath2 , Penna Balakrishna2 , Aparna Ravi 3 , J. Kalaivannan4

    Affiliation(s) Name:

    1 Department of Anatomy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India,

    2 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India,

    3 Department of Pharmacology, Azeezia Institute of Medical Sciences, Kerala, Karnataka, India,

    4 Department of Anatomy, Vinayaka Mission Medical College, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India

    *Corresponding Author: Mudiganti Ram Krishna Rao, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

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    Author:

    K. Prabhu1 , Mudiganti Ram Krishna Rao2 *, S. K. Vishal 2 , A. K. Bharath2 , Penna Balakrishna2 , Aparna Ravi 3 , J. Kalaivannan4

    Title:Gas chromatography–mass spectrometry study of one Ayurvedic Rasayana drug, Dhanwantari Rasayanam
    Journal:Drug Invention Today
    Vol(issue):14 (May)
    Year:2020
    Page No: (783-786)
  • Experimental Methods Keywords

    Methodology: Gas chromatography–mass spectrometry
    Research Materials:Ayurvedic, Dhanwantari Rasayanam

Keywords

Beta.-Asarone 5-Hydroxymethylfurfural Ayurvedic Dhanwantari Rasayanam Gas chromatography–mass spectrometry Hemiplegia Heptanediamide Hexadecanoic acid Oleic acid Paraplegia

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