Journal: Drug Invention Today

Article Id: JPRS-DFP-00005069
Title: Biosynthesis of silver nanoparticles with Mentha spicata against Aspergillus niger
Category: Drugs from Plants
Section: Research Article
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    Background: Mentha spicata not modern uses aqueous leaf extract of medicinal plant. Silver nanoparticles(AgNPs) synthesized by leaves of Mentha spicata were evaluated for antimicrobial activity and found highly toxic and hazardous to microorganisms. It is found out that the silver nanoparticles have many inhibitory and fungicidal effects and so its application is extended as an antibacterial agent. The antifungal activity of silver nanoparticles is estimated by the zone of inhibition. Aspergillus sp. are indoor and outdoor saprophytic fungi that play a significant role in global carbon and nitrogen recycling while negatively in human and animal. Materials and Methods: After the addition of AgNO3 within 20 min, the suspension showed change in color and turned dark brown, formation of silver nanoparticles was confirmed using ultraviolet (UV) spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and field emission scanning electron microscopy (FESEM). In this study, 70 samples were collected from sputum, 44 males and 26 females. Samples were positive 32 males and 18 females (50 infection) for the presence of fungal element. Results: Structure of synthesized AgNPs were confirmed by FTIR, UV visible, XRD and FESEM studies. Fungal species were isolated from sputum and bronchoalveolar lavage fluids. Many species were recovered and the effect nanoparticles on Aspergillus niger growth were tested. The result showed the effectivity of nanoparticles against fungus with zone of inhibition with 8 mm at concentration of 20 mg. Conclusions: The possibility of preparing nanoparticles of M. spicata plant using silver nitrate (AgNO3 ) result revealed that AgNPs have a good activity against aspergillosis.

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    Author(s) Name:

    Fatema M. A. Alkfaji*, Ibtihal Muiz Al Hussaini

    Affiliation(s) Name:

    Department of Biology, College of Sciences, University of Babylon, Babil, Iraq

    *Corresponding author: Fatema M. A. Alkfaji, Department of Biology, College of Sciences, University of Babylon, Babil, Iraq.

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    Author:

    Fatema M. A. Alkfaji*, Ibtihal Muiz Al Hussaini

    Title:Biosynthesis of silver nanoparticles with Mentha spicata against Aspergillus niger
    Journal:Drug Invention Today
    Vol(issue):14 (June )
    Year:2020
    Page No: (806-811)
  • Experimental Methods Keywords

    Methodology:Fourier transform infrared, FSEM, X-ray diffraction
    Research Materials:Mentha spicata, Nanoparticles

Keywords

AgNO3 Aspergillus niger Fourier transform infrared FSEM Mentha spicata Nanoparticles X-ray diffraction

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