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Abstract

The emergence of controlled release (CR) technology as an effective way to enhance patient compliance and extend the life cycle of a drug has led to the need for novel ways of controlling the drug release profiles. Polymers present a logical and simple approach to control the release of drugs. Natural and synthetic polymers serve as key excipients in oral and parenteral CR formulations. The use of natural excipients for controlled deliver of the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. This article gives an overview of natural excipients which are used in controlled drug delivery systems.

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	JPR Solutions

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