Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000533
Title: Antipyretic Activity of Different Fractions of Root Extract of Smilax chinensis Linn. (Liliaceae) in Albino Rats
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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  • Abstract

    Antipyretic effect of chloroform, ethyl acetate and methanol soluble fractions of methanol extract of the roots of Smilax chinensis Linn. was investigated. Animals were given a subcutaneous injection of 10 ml/kg body wt. of 15 % w/v yeast suspended in 0.5% w/v methylcellulose solution which leads to pyrexia. Oral administration of chloroform, ethyl acetate and methanol soluble fractions of methanol extract of the roots of Smilax chinensis Linn. at a dose 50 mg/kg body weight into three groups of animal were shown significantly reduce the elevated body temperature of rat which was compared with standard aspirin (market product) and solvent used.

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    Author(s) Name:

    Goutam Kumar Jana 1*, S.Mondal2, Sanchita Das2, Ranabir Sahu2, Pallab Kanti Haldar 2, Saikat Dewanjee2

    Affiliation(s) Name:

    *1Department of Pharmacognosy, Gayatri College of Pharmacy, Jamadarpali, Sason,
    Sambalpur, Orissa, 768200
    2 Department of Pharmaceutical Technology, Jadavpur University, Kolkata-700032


    Received on: 09-02-2009; Accepted on: 17-03-2009

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    Author:

    Goutam Kumar Jana 1*, S.Mondal2, Sanchita Das2, Ranabir Sahu2, Pallab Kanti Haldar 2, Saikat Dewanjee2

    Title:Antipyretic Activity of Different Fractions of Root Extract of Smilax chinensis Linn. (Liliaceae) in Albino Rats
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (June)
    Year:2009
    Page No: (1026-1027)
  • Experimental Methods Keywords

    Methodology:Antipyretic activity
    Research Materials:Smilax chinensis

Keywords

Smilax chinensis Antipyretic activity Albino Rat Yeast Aspirin

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