Journal: Journal of Pharmacy Research

Article Id: JPRS-PB-0000538
Title: Medicinal plants as alternative biocontrol agents in the control of seed borne pathogen Macrophomina phaseolina
Category: Pharmaceutical Biotechnology
Section: Research Article
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  • Abstract

    In a search for plant extracts with potent antifungal activity against plant pathogenic fungi, the methanol extracts of different medical plants effectively controlled the development of plant diseases caused by Macrophomina phaseolina. The methanolic extracts of forty nine plants hexane, chloroform and methanolic extracts were used for the study, among them methanolic extracts of forty eight medicinal plants exhibited varying degrees of inhibition activity against M. phaseolina, extracts of Tephrosia pumila have no activity. Extracts of Avicenia officinales, Cleome viscose, Grewia arborea, Hyptis sueolences, Ocimum sanctum, Peltophorum pterophorus, Sesbanian grandiflora, Terminalia chebula, Tephrosia pumila, Tephrosia villosa, Withania somnifera showed high activity and Terminalia chebula having strong antifungal activity against M. phaseolina even at low concentrations. Chloroform extracts has very low antimicrobial activity where as hexane has no antimicrobial properties.

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    Author(s) Name:

    *Varaprasad Bobbarala,*Rajesh Kumar Chadaram,***Varahalarao Vadlapudi and **Prasanth Kumar Katikala.

    Affiliation(s) Name:

    *For U Biosciences, A/4A, Park lane Residency, East point colony, Visakhapatnam, A. P-530017, India.
    **Pharmaceutical Biotechnology Division, A. U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003.
    ***Department of Botany, Andhra University, Visakhapatnam-530003


    Received on: 27-02-2009; Accepted on: 29-04-2009

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    Author:

    *Varaprasad Bobbarala,*Rajesh Kumar Chadaram,***Varahalarao Vadlapudi and **Prasanth Kumar Katikala.

    Title:Medicinal plants as alternative biocontrol agents in the control of seed borne pathogen Macrophomina phaseolina
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (June)
    Year:2009
    Page No: (1045-1048)
  • Experimental Methods Keywords

    Methodology:Antifungal activity,Minimum inhibitory concentration (MIC) assays
    Research Materials:Macrophomina phaseolina

Keywords

Macrophomina phaseolina Crude methanolic extracts Antifungal activity Potato Dextrose Agar (PDA) Well diffusion assay.

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