Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-000054
Title: Pharmaceutical Application of Supercritical Fluid Technique: An overview
Category: Pharmaceutics
Section: Research Article
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    Particle design of active pharmaceutical ingredients is important to make the solid dosage forms with suitable physicochemical properties. Supercritical carbon dioxide has been used for the purpose of micronization, polymorphic control, preparation of solid dispersion and complexes. Control of the characteristic properties of particles such as size, shape, crystal structure and morphology is required to optimize the formulation. For solubility enhancement of poorly water-soluble drugs, preparation of the solid dispersion or the complexation with proper drugs or excipients should be a promising approach by Supercritical fluid technique also have been exploited in extraction, separation and crystallization processes.

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    Author(s) Name:

    A.V.Yadav* and  V. B. Yadav

    Affiliation(s) Name:

    Govt.College of Pharmacy, Karad, 415124, (Maharashtra). India.


    For correspondence:A.V.Yadav and V. B. Yadav,Govt.College of Pharmacy, Karad, 415124, (Maharashtra). India.


    E-mail: avyadav03@rediffmail.com,

               venkat_yadav3@rediffmail.com


    Received on: 10-07-2008; Accepted on :22-10-2008

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    Author:

    A.V.Yadav* and  V. B. Yadav

    Title:Pharmaceutical Application of Supercritical Fluid Technique: An overview
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (January )
    Year:2009
    Page No: (31-44)
  • Experimental Methods Keywords

    Methodology:Supercritical fluid technique
    Research Materials:-

Keywords

Supercritical fluid technique Dispersion Solubility Crystallization Extraction Dissolution

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