Journal: Journal of Pharmacy Research

Article Id: JPRS-QA-0000542
Title: Simultaneous determination of Finasteride and Tamsulosin in pharmaceutical preparations by ratio derivative spectroscopy
Category: Quality Assurance
Section: Research Article
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  • Abstract

    Simple, accurate, precise, and sensitive spectrophotometric method for simultaneous estimation of Tamsulosin(TAM) and Finasteride(FINA) in combined tablet dosage form have been developed and validated. The ratio derivative spectroscopic method involves measurement of first derivative amplitude of ratio spectra at 240.01nm for FINA and 229.91 nm for TAM as two wavelengths for estimation. Beer’s law is obeyed in the concentration range of 2-10 and 25-125 μg/mL for TAM and FINA, respectively.

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    Author(s) Name:

    Atul H. Kategaonkar1, Dhaval M. Patel, Vishnu P. Choudhari1*, Bhanudas S. Kuchekar1, Ana G. Nikalje2.

    Affiliation(s) Name:

    1. Pharmaceutical Analysis and Quality Assurance Dept.,MAEER’S Maharashtra Institute of Pharmacy, S.No. 124, MIT Campus, Paud Road, Kothrud, Pune-411038, India.
    2. Post-graduate Department of Pharmaceutical Chemistry, Y.B. Chavan College of Pharmacy, Dr. Rafiq Zakaria Campus, Rauza Bagh, Aurangabad.431001. MS. India


    Received on: 27-02-2009; Accepted on: 29-04-2009

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    Author:

    Atul H. Kategaonkar1, Dhaval M. Patel, Vishnu P. Choudhari1*, Bhanudas S. Kuchekar1, Ana G. Nikalje2.

    Title:Simultaneous determination of Finasteride and Tamsulosin in pharmaceutical preparations by ratio derivative spectroscopy
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (June)
    Year:2009
    Page No: (1065-1067)
  • Experimental Methods Keywords

    Methodology:Simultaneous determination,Spectroscopy
    Research Materials:Tamsulosin, Finasteride

Keywords

Tamsulosin Finasteride Ratio Derivative Spectroscopy.

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