Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000544
Title: Evaluation of antimicrobial and antioxidant properties of Momordica dioica Roxb. (Ex Willd)
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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    Momordica dioica Roxb is a perennial climbing creeper belonging to the family Curcurbitaceae and generally found in the forests of Southern India, Bengal, Maharashtra and Madhya Pradesh. In the present study the methanolic extract (MEFMD) and aqueous extract (AEFMD) of fruits of Momordica dioica Roxb were analyzed for the presence of different phytochemical constituents and total phenolic content. MEFMD after drying on rotary evaporator was used for screening of antimicrobial and antioxidant properties. The screening of antimicrobial activity was done using reported disc diffusion method on common gram positive and gram negative bacteria whereas DPPH (2,2-Diphenyl- 1-Picrylhydrazyl) and Nitrous oxide method was used to evaluate antioxidant activities of extract. The MEFMD showed the presence of phenolic compound, flavonoids and sterol whereas AEFMD showed the presence of flavonoids, glycosides, alkaloids and amino acids. Total phenolic content was expressed as GAE (Gallic acid equivalent) in mg per gram dry weight of sample. MEFMD showed more promising antimicrobial and antioxidant activity as compared to AEFMD.

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    Author(s) Name:

    Bumrela Shrinivas*,1, Samleti Anil1, Melisa Parera1 and Manisha Saxena1

    Affiliation(s) Name:

    1Sinhgad Institute Pharmaceutical Sciences, Kusgaon (Bk), Lonavala. Pune 410401, India


    Received on: 23-01-2009; Accepted on 11-03-2009

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    Author:

    Bumrela Shrinivas*,1, Samleti Anil1, Melisa Parera1 and Manisha Saxena1

    Title:Evaluation of antimicrobial and antioxidant properties of Momordica dioica Roxb. (Ex Willd)
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (June)
    Year:2009
    Page No: (1075-1078)
  • Experimental Methods Keywords

    Methodology:Antibacterial, Antioxidant.
    Research Materials:Momordica dioica Roxb,

Keywords

Momordica dioica Roxb Antibacterial Antioxidant.

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