Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-0000551
Title: Microwave one-step synthesis and evaluation of antimicrobial activities of new fused [1,8]naphthyridine derivatives
Category: Pharmaceutical Chemistry
Section: Research Article
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  • Abstract

    A simple and efficient procedure has been described for the synthesis of benzo [g]naphtho[b][1,8]naphthyrindes 3 by the condensation of 2- chloro-3-formylquinoline 1 with 1-naphthylamine 2 under microwave irradiation condition. The structures of the newly synthesized compounds were confirmed by analytical and spectral (IR, NMR, and Mass) data. All these compounds were evaluated for their in vitro growth-inhibitory activity against several microbes.

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    Author(s) Name:

    Vetrivel Nadaraj1, Senniappan Thamarai Selvi 1* and Sellappan Mohan2

    Affiliation(s) Name:

    1Department of Chemistry (PG and Research),Kongunadu Arts and Science College, G.N. Mills Post Coimbatore - 641 029,INDIA
    2Department of Pharmaceutics, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar- 382 355, INDIA


    Received on:14-02-2009; Accepted on: 18-04-2009

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    Author:

    Vetrivel Nadaraj1, Senniappan Thamarai Selvi 1* and Sellappan Mohan2

    Title:Microwave one-step synthesis and evaluation of antimicrobial activities of new fused [1,8]naphthyridine derivatives
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (June)
    Year:2009
    Page No: (1120-1123)
  • Experimental Methods Keywords

    Methodology:Microwave one-step synthesis and evaluation of antimicrobial activities
    Research Materials:new fused [1,8]naphthyridine derivatives

Keywords

Naphthylamine Microwaves Naphthyridines Condensation Anti-microbial activity.

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