Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000560
Title: In-vitro Anthelmintic Activity of Seed Extract of Lagenaria siceraria (Molina.) Standley Fruit
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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  • Abstract

    The aim of present study was to evaluate anthelmintic potential of crude extracts of seeds of Lagenaria siceraria (Molina) Standley using Pheretima posthuma as test worms. Various concentrations (10 – 100 mg/ml) of the extracts were tested in the bioassay, which involved determination of time of paralysis (P) and time of death (D) of the worms. Piperazine citrate (10 mg/ml) was included as standard reference and distilled water as control. The results of present study indicated that the methanol and benzene extracts significantly demonstrated paralysis, and also caused death of worms especially at higher concentration of 100 mg/ml, as compared to standard reference Piperazine citrate. In conclusion, the traditional use of seeds of the plant Lagenaria siceraria as an anthelmintic have been confirmed and further studies are suggested to isolate the active principle/s responsible for the activity.

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    Author(s) Name:

    Thube Smita 1*, Tambe Rashmi1, Patel Mohammed Farooque 1, Patel Sakil Daud1

    Affiliation(s) Name:

    Department of Pharmacognosy, M.C.E.Society’s Allana College of Pharmacy, Azam Campus , 2390 K.B.Hidyatullah road, Camp, Pune 411 001.India


    Received on: 17-02-2009; Accepted on: 19-04-2009

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    Author:

    Thube Smita 1*, Tambe Rashmi1, Patel Mohammed Farooque 1, Patel Sakil Daud1

    Title:In-vitro Anthelmintic Activity of Seed Extract of Lagenaria siceraria (Molina.) Standley Fruit
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (July)
    Year:2009
    Page No: (1194-1195)
  • Experimental Methods Keywords

    Methodology:In-vitro Anthelmintic Activity,
    Research Materials: Lagenaria siceraria, Pheretima posthuma

Keywords

Anthelmintic Lagenaria siceraria Pheretima posthuma Piperazine citrate.

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