Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000564
Title: Development of UV-spectroscopic method for nabumetone in tablet formulation
Category: Pharmaceutics
Section: Research Article
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  • Abstract

    Nabumetone is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of nabumetone from bulk and tablet formulation. The drug obeyed the Beer’s law and showed the regression line (Y = 0.024 X – 0.003) and correlation coefficient 0.9998. It showed absorption maxima at 261 nm; in methanol. The linearity was observed between 5 – 45 μg/mL. The results of analysis were validated by recovery studies. The % recovery was found to be 99.2 – 100.2%. The method was found to be simple, accurate, precise, economical and robust.

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  • About the authors and Affiliations

    Author(s) Name:

    A.H. Mohite* and A. Peepliwal1

    Affiliation(s) Name:

    *School of Pharmacy and Technology Management,Babulde, Near Bank of Tapi river, Shirpur,Dist: Dhule, (M.S) India 425 405
    1School of Pharmacy and Technology Management,Babulde, Near Bank of Tapi river, Shirpur,Dist: Dhule, (M.S) India 425 405


    Received on: 07-02-2009; Accepted on: 09-04-2009

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    Author:

    A.H. Mohite* and A. Peepliwal1

    Title:Development of UV-spectroscopic method for nabumetone in tablet formulation
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (July)
    Year:2009
    Page No: (1221-1223)
  • Experimental Methods Keywords

    Methodology:UV-spectroscopic method
    Research Materials:Nabumetone

Keywords

Nabumetone UV–Vis Spectrophotometry Recovery Validation

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