Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000568
Title: Phytosomes: a potential phyto-phospholipid carriers for herbal drug delivery
Category: Pharmaceutics
Section: Review Article
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  • Abstract

    The potential uses of large number of herbal drugs are limited due to their poor absorption and poor bioavailability after oral administration. The bioavailability can be improved by formulating a appropriate drug delivery system, which can enhance the rate and the extent of drug absorption across the lipoid biomembrane. Phospholipids based drug delivery system have been found promising for better and effective delivery of drug and providing much appropriate systematic drug delivery. The phospholipid molecular structure includes a water-soluble head and two fat-soluble tails, because of this dual solubility, the phospholipid acts as an effective emulsifier, which is also one of the chief components of the membranes in our cells. “Phytosome” is formed by complexing the polyphenolic phytoconstituents in molar ratio with phosphatidylcholine. Phytosomes are advanced forms of herbal products that are better absorbed, utilized, and as a result produce better drug delivery than conventional herbal extracts. This article reviews the current trends in phytosomes drug delivery.

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  • About the authors and Affiliations

    Author(s) Name:

    Nitesh S Chauhan*1, Gowtham Rajan2, B. Gopalakrishna1

    Affiliation(s) Name:

    1Department of Pharmaceutics, R R College of Pharmacy, Bangalore-560090
    2Departmet of Pharmacy, Karpagam University, Coimbatore-641 021


    Received on: 27-02-2009; Accepted on: 29-04-2009

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    Author:

    Nitesh S Chauhan*1, Gowtham Rajan2, B. Gopalakrishna1

    Title:Phytosomes: a potential phyto-phospholipid carriers for herbal drug delivery
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (July)
    Year:2009
    Page No: (1267-1270)
  • Experimental Methods Keywords

    Methodology:Drug Delivery
    Research Materials:Phytosomes

Keywords

Phytosomes Phospholipids Drug Delivery

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