Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-000057
Title: Antidiabetic activity of the aqueous extract of Chlorophytum borivilianum L. In Streptozotocin induced- hyperglycemic rats- A preliminary study
Category: Pharmacognosy and Herbal Drugs related study
Section: Editorial
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  • Abstract

    The aqueous extract of roots of Chlorophytum borivilianum L. at a dose of 250 mg/kg and 500 mg/kg body weight respectively was tested for antidiabetic activity in streptozotocin (STZ)- induced hyperglycaemic rats. The blood glucose levels were measured at 0, 2h, 4h and 6h after the treatment. The aqueous extract reduced the blood glucose in STZ- induced diabetic rats from 285.56 to 206.82 mg/dl, 6h after oral administration of extract (P<0.01). The antidiabetic activity of aqueous extract of Chlorophytum borivilianum was compared with glibenclamide, an oral hypoglycaemic agent (3mg/kg).

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    Author(s) Name:

    Mohd. Mujeeb *1, Shah Alam Khan 2, Mohd. Ali 1, Abhishek Mall1 and

    Aftab Ahmad2

    Affiliation(s) Name:

    *1Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062, India.


    2Jeddah Community College, King Abdul Aziz University, Jeddah, Kingdom of Saudi Arabia


    *For correspondence:Mohd. Mujeeb ,Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062, India


    E-mail:shahalamkhan@yahoo.com, mujeeb_zaidi@yahoo.co.in


    Received on:09-08-2008; Accepted on :04-11-2008

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    Author:

    Mohd. Mujeeb *1, Shah Alam Khan 2, Mohd. Ali 1, Abhishek Mall1 and

    Aftab Ahmad2

    Title:Antidiabetic activity of the aqueous extract of Chlorophytum borivilianum L. In Streptozotocin induced- hyperglycemic rats- A preliminary study
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (January )
    Year:2009
    Page No: (51-53)
  • Experimental Methods Keywords

    Methodology:Antidiabetic activity,STZ induced hyperglycemia,
    Research Materials:Chlorophytum borivilianum

Keywords

Antidiabetic activity Chlorophytum borivilianum Streptozotocin Glibenclamide.

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