Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000585
Title: RP-HPLC Estimation of Aspirin and Atorvastatin Calcium in Combined Dosage Forms
Category: Pharmaceutics
Section: Research Article
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    A reverse phase high performance liquid chromatography method was developed for simultaneous estimation of aspirin and atorvastatin calcium in capsule formulation. The separation was achieved by RP-18 column and methnol:water pH 6.0 (60:40v/v) as eluent, at flow rate 1.0 ml/min. Detection was carried out at 242nm. The retention time of aspirin and atorvastatin calcium was found to be 1.98 and 7.99 min, respectively. The method was validated for linearity, accuracy and precision. Linearity for aspirin and atorvastatin calcium were in the range of 4-20 μg/ml. The developed method was found to be accurate, precise, and selective for simultaneous estimation of aspirin and atorvastatin calcium in capsules.

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    Author(s) Name:

    G. F. Patel1*, N. R. Vekariya2, R. B. Dholakiya3, G. K. Ramani4

    Affiliation(s) Name:

    1, 2, 3 & 4Shree Dhavantary Pharmacy College, Kim, India.


    Received on:12-04-2009; Accepted on: 09-06-2009

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    Author:

    G. F. Patel1*, N. R. Vekariya2, R. B. Dholakiya3, G. K. Ramani4

    Title:RP-HPLC Estimation of Aspirin and Atorvastatin Calcium in Combined Dosage Forms
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (August)
    Year:2009
    Page No: (1274-1275)
  • Experimental Methods Keywords

    Methodology:RP-HPLC, Estimation, and Capsules.
    Research Materials:Atorvastatin cacium

Keywords

Atorvastatin cacium Aspirin RP-HPLC Estimation and Capsules.

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