Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-000059
Title: In vitro free radicals scavenging activity of stems of Cuscuta reflexa
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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    Cell damage caused by free radicals appears to be a major contributor to aging and to degenerative diseases of aging such as cancer, cardiovascular disease, cataracts, immune system decline, and brain dysfunction. Overall, free radicals have been implicated in the pathogenesis of many disease. Cuscuta Reflexa plant reported to have in vitro antioxidant activity (non-enzymatic hemoglobin glycosylation), antibacterial activity, onset of puberty and ovarian steroidogenesis The aim of the present study to evaluate the free radicals scavenging activity by using DPPH radical scavenging assay and reducing power assay of methanolic extract of Cuscuta Reflexa (MECR). The DPPH assay results were expressed as IC50 value. Ascorbic acid which was used as a standard showed an IC50 9.22μg/ml, whereas, the methanolic extract of Cuscuta Reflexa (MECR) showed antioxidant activitywith IC50 value 359.48μg/ml. The reducing power of MECR was found to be increase with increasing amount of extract concentration. All the concentrations of MECR showed significant antioxident activities when compared to control and these differences were statistically significant (p < 0.001)

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    Author(s) Name:

    Patil Amol*, Patil Vikas, Chaudhari Kundan, Patil Vijay, Chaudhari Rajesh

    Affiliation(s) Name:

    *TVES’s College of Pharmacy, Faizpur, Tal. Yawal Dist. Jalgaon-425503 (Maharashtra) ,India


    For correspondence:Patil Amol ,MotheWaghode Tal: Raver Dist: Jalgaon ,425502 ( Maharastra),India.


    E-mail: amolpatil311@gmail.com,

                amolppatil2003@rediffmail.com


    Received on:17-08-2008; Accepted on :19-11-2008

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    Author:

    Patil Amol*, Patil Vikas, Chaudhari Kundan, Patil Vijay, Chaudhari Rajesh

    Title:In vitro free radicals scavenging activity of stems of Cuscuta reflexa
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (January )
    Year:2009
    Page No: (58-61)
  • Experimental Methods Keywords

    Methodology:FREE RADICAL SCAVENGING ACTIVITY,
    Research Materials:Cuscuta Reflexa

Keywords

Cuscuta Reflexa antioxidant activity DPPH assay Ascorbic Acid

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