Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000607
Title: Antiulcer activity of Melia azedarach linn in aspirin induced and pylorus ligated rats
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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    In the present study aqueous and alcohol extracts of leaves of Melia azedarach Linn. (Meliaceae) were screened for antiulcer activity in aspirin induced and pylorus – ligated rats. The effect was assessed by parameters like pH, free acidity, total acidity and ulcer index. Aqueous extract and alcohol extract of M. azedarach leaves (250 mg/kg b.w., p.o.) were administered orally. Antiulcer effects were compared with standard drug Omeprazole (20 mg/kg b.w., p.o.). These observations helped us to conclude that aqueous extract (250 mg/kg b.w., p.o.) is endowed with antiulcer property.

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    Author(s) Name:

    Yogendr Bahuguna*1, Kalpana Patil2, Mohan Singh Maniyari Rawat3, Sunil Jalalpure2, Sampada Uniyal1

    Affiliation(s) Name:

    *1Division of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology and Sciences, Patel Nagar, Dehradun-248001, Uttarakhand, India
    2Department of Pharmacognosy and Phytochemistry, K.L.E.S.’s College of Pharmacy, Belgaum-10, Karnataka, India
    3Department of Chemistry, H.N.B. Garhwal University, Srinagar, Pauri Garhwal, Uttarakhand, India


    Received on: 20-05-2009; Accepted on:15-07-2009

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    Author:

    Yogendr Bahuguna*1, Kalpana Patil2, Mohan Singh Maniyari Rawat3, Sunil Jalalpure2, Sampada Uniyal1

    Title:Antiulcer activity of Melia azedarach linn in aspirin induced and pylorus ligated rats
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (September)
    Year:2009
    Page No: (1456-1459)
  • Experimental Methods Keywords

    Methodology:Antiulcer;Pylorus - ligation.
    Research Materials:Melia azedarach

Keywords

Antiulcer; Aspirin; Melia azedarach; Omeprazole; Pylorus - ligation.

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