Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000609
Title: RP-HPLC method development for determination of pioglitazone hydrochloride from tablets
Category: Pharmaceutics
Section: Research Article
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  • Abstract

    A simple, rapid and precise reversed-phase HPLC method has been developed for the quantitation of pioglitazone in tablet on a C-8 (mm) column using a mobile phase consisting acetonitrile-water(60:40 %v/v) adjusted to ph 6.0 with 0.1 % v/v glacial acetic acid solution at a flow rate of 1 ml/min and detection at 266 nm. The retention time of pioglitazone have been found to be 6.40 min and recoveries were between 98.82- 101.21 %. Validation of the proposed method has also been done.

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    Author(s) Name:

    S .Sayed*, A. Thomas, L. Kotapali

    Affiliation(s) Name:

    Allana College of Pharmacy, Camp, Pune

    Received on: 24-05-2009; Accepted on:15-07-2009

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    Author:

    S .Sayed*, A. Thomas, L. Kotapali

    Title:RP-HPLC method development for determination of pioglitazone hydrochloride from tablets
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (September)
    Year:2009
    Page No: (1479-1480)
  • Experimental Methods Keywords

    Methodology:HPLC Method
    Research Materials:Pioglitazone (Pio)

Keywords

Pioglitazone (Pio) Metformin (Met) HPLC CAN glacial acetic acid

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