Journal: Journal of Pharmacy Research

Article Id: JPRS-PP-0000629
Title: Isolation and Characterization of New Lanosteriod from Ethanolic Extract of Eclipta alba Linn.
Category: Pharmacognosy and Phytochemistry,
Section: Research Article
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  • Abstract

    In present investigations, whole plant of Eclipta alba was extracted in soxhlet apparatus using 95% ethanol as solvent. The dried ethanolic extract of Eclipta alba Linn.  was further eluted with mobile phase of petroleum ether: chloroform (1:6) using silica gel column to elute compound 1 i.e. terpenoids (Identified by thin layer chromatography). The compound 1 was subjected to spectroscopic studies (IR, PNMR, 13CNMR and Mass spectroscopy) for structure elucidation. On the basis of the spectral data analysis and chemical reactions, the structure of compound 1 has been established as lanost – 5, 24 – dien – 3 β– ol – 18, 21 – olide -3 β- yl tetradecanoate (a lanosteroid).

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    Author(s) Name:

    Kadambari Tomer *1, Vijendra Singh1, Neeraj Kumar Sethiya2, Mukesh Kumar2, Durga Jaiswal3, Indranil Kumar Yadav4, Hari Pratap Singh4, Dinesh Chandra4 and D.A. Jain4

    Affiliation(s) Name:

    *1 Ram-Eesh Institute of Vocational and Technical Education, Greater Noida - 201306
    2Pharmacy Department, Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat- 390 001, India.
    3Rajiv Gandhi College of Pharmacy, Nautanwa, Maharajganj-273164, India.
    4Institute of Pharmaceutical Sciences and Research Centre, Bhagwant University, Ajmer-305001, India.


    Received on: 14-06-2009; Accepted on:17-08-2009

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    Author:

    Kadambari Tomer *1, Vijendra Singh1, Neeraj Kumar Sethiya2, Mukesh Kumar2, Durga Jaiswal3, Indranil Kumar Yadav4, Hari Pratap Singh4, Dinesh Chandra4 and D.A. Jain4

    Title:Isolation and Characterization of New Lanosteriod from Ethanolic Extract of Eclipta alba Linn.
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (October)
    Year:2009
    Page No: (1635-1637)
  • Experimental Methods Keywords

    Methodology:Isolation and Characterization
    Research Materials:Eclipta alba

Keywords

Eclipta alba chromatography terpenoids lanosteroid.

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