Journal: Journal of Pharmacy Research
Title: In-vitro Antioxidant Activity of methanolic extract of Aerial Parts of Canna indica L.
Category: Pharmacognosy and Herbal Drugs related study
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Abstract
The requirement of compound with antioxidant activity is increasing as there is realization of that formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been linked in pathogenesis of several human diseases. The herb Canna indica L. is commonly known as Devkali, which is widely used in the indigenous system of medicine for the treatment of diuretic, fevers and dropsy. The aerial parts methanolic extract of the plant was studied for its in vitro antioxidant activity in different methods viz DPPH radical scavenging assay, Nitric oxide scavenging assay, Hydrogen peroxide Assay, Hydroxl radical scavenging Assay. Its free radical scavenging activity was estimated by IC50 value and the values at various concentrations 10 to 100ìg/ml. At 100µg/ml DPPH radical scavenging assay, Hydroxyl radical scavenging assay, Hydrogen peroxide assay and Nitric oxide assay showed maximum inhibition76.70% ,74.36%, 61.37% and 62.84% These results clearly indicate that Aerial Parts of Canna indica is effective in scavenging free radicals and has the potential to be a powerful antioxidant.
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About the authors and Affiliations
Author(s) Name: Yadunath M. Joshi, Vilasrao J. Kadam and Prashant R.Kaldhone*
Affiliation(s) Name: *Bharati Vidyapeeth’s College of Pharmacy, CBD Belapur, Navi Mumbai400614
Received on: 20-05-2009; Accepted on:15-07-2009-
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Author: Yadunath M. Joshi, Vilasrao J. Kadam and Prashant R.Kaldhone*
Title: In-vitro Antioxidant Activity of methanolic extract of Aerial Parts of Canna indica L. Journal: Journal of Pharmacy Research Vol(issue): 2 (November) Year: 2009 Page No: (1712-1715) -
Experimental Methods Keywords
Methodology: In-vitro Antioxidant Activity Research Materials: Canna indica L
Keywords
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