Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000636
Title: In-vitro Antioxidant Activity of methanolic extract of Aerial Parts of Canna indica L.
Category: Pharmacognosy and Herbal Drugs related study
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  • Abstract

    The requirement of compound with antioxidant activity is increasing as there is realization of that formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been linked in pathogenesis of several human diseases. The herb Canna indica L. is commonly known as Devkali, which is widely used in the indigenous system of medicine for the treatment of diuretic, fevers and dropsy. The aerial parts methanolic extract of the plant was studied for its in vitro antioxidant activity in different methods viz DPPH radical scavenging assay, Nitric oxide scavenging assay, Hydrogen peroxide Assay, Hydroxl radical scavenging Assay. Its free radical scavenging activity was estimated by IC50 value and the values at various concentrations 10 to 100ìg/ml. At 100µg/ml DPPH radical scavenging assay, Hydroxyl radical scavenging assay, Hydrogen peroxide assay and Nitric oxide assay showed maximum inhibition76.70% ,74.36%,  61.37% and 62.84% These results clearly indicate that Aerial Parts of Canna indica is effective in scavenging free radicals and has the potential to be a powerful antioxidant.

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    Author(s) Name:

    Yadunath M. Joshi, Vilasrao J. Kadam and  Prashant R.Kaldhone*

    Affiliation(s) Name:

    *Bharati Vidyapeeth’s College of Pharmacy, CBD Belapur, Navi Mumbai400614


    Received on: 20-05-2009; Accepted on:15-07-2009

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    Author:

    Yadunath M. Joshi, Vilasrao J. Kadam and  Prashant R.Kaldhone*

    Title:In-vitro Antioxidant Activity of methanolic extract of Aerial Parts of Canna indica L.
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (November)
    Year:2009
    Page No: (1712-1715)
  • Experimental Methods Keywords

    Methodology:In-vitro Antioxidant Activity
    Research Materials:Canna indica L

Keywords

Aerial Parts Canna indica Free Radical Scavenging Antioxidant

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