Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000638
Title: Lipid lowering activity of Abutilon indicum (L.) leaf extracts in rats
Category: Pharmacology
Section: Research Article
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  • Abstract

    Lipid lowering effect of the successive extracts of the leaf of Abutilon indicum (L.)  was evaluated in triton and diet induced hyperlipidemic models of wistar albino rats. The ethanolic and water extract at 400mg/kg dose levels inhibited the elevation in serum cholesterol and triglyceride levels on Triton WR 1339 administration rats. The extracts at the same dose level significantly attenuated the elevated serum total cholesterol and triglycerides with an increase in high-density lipoprotein cholesterol in high-fat diet-induced hyperlipidemic rats. The standard dose Atrovastatin in the former and Gemfibrozil in the later studies showed slightly better effects.

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    Author(s) Name:

    Ranjan Kumar Giri *1, Sunil Kumar Kanungo1, V.Jagannath Patro2, Sujit Dash1, Durga Charan Sahoo3

    Affiliation(s) Name:

    *1Department of Pharmacology,Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India
    2 Department of Pharmachemistry,College of Pharmaceutical Sciences, Mohuda, Berhampur, Orissa. India
    3Department of Pharmacognosy,Dadichi College of Pharmacy, Vidya Vihar, Cuttack, Orissa, India

    Received on: 20-05-2009; Accepted on:15-07-2009

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    Author:

    Ranjan Kumar Giri *1, Sunil Kumar Kanungo1, V.Jagannath Patro2, Sujit Dash1, Durga Charan Sahoo3

    Title:Lipid lowering activity of Abutilon indicum (L.) leaf extracts in rats
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (November)
    Year:2009
    Page No: (1725-1727)
  • Experimental Methods Keywords

    Methodology:Antihyperlipidemic activity
    Research Materials:Abutilon indicum

Keywords

Abutilon indicum Antihyperlipidemic activity High-fat diet Triton WR 1339 HDL-C Triglycerides

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