Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000653
Title: Antiulcer activity of aqueous suspension of Saraca indica flower against gastric ulcers in albino rats
Category: Pharmacology
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  • Abstract

    The effect of aqueous suspension of Saraca indica flower was investigated in albino rats to evaluate the anticulcer activity by using two models, i.e., pyloric ligation and aspirin induced gastric ulcer. The parameters taken to assess antiulcer activity were free and total acidity and ulcer index. The control group received 2 ml of normal saline and varying doses of the Saraca indica flower extract were used for the remaining group (10–30 mgkg-1 b.w.). The results indicate that the aqueous flower extract Saraca indica significantly (P<0.005) decreases the free and total acidity and ulcer index with respect to control in a dose dependent manner thus justifying the use of Saraca indica flower extract as an antiulcer agent in folklore medicine.

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    Author(s) Name:

    V. Maruthappan1 and K. Sakthi Shree2

    Affiliation(s) Name:

    1Unit of Endocrinology, Department of Zoology, Bharathiar University, Coimbatore,T.N. India.

    2Department of Zoology, Govt. Arts College (Autonomous), Coimbatore,T.N. India

    Received on: 20-09-2009; Revised on: 16-10-2009; Accepted on:15-12-2009

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    Author:

    V. Maruthappan1 and K. Sakthi Shree2

    Title:Antiulcer activity of aqueous suspension of Saraca indica flower against gastric ulcers in albino rats
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (January)
    Year:2010
    Page No: (17-20)
  • Experimental Methods Keywords

    Methodology:Antiulcer activity
    Research Materials:Saraca indica

Keywords

Saraca indica antiulcer pyloric ligation aspirin

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