Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000669
Title: Antioxidant efficacy of Cynodon dactylon leaf protein against ela implanted swiss albino mice
Category: Pharmacology
Section: Research Article
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  • Abstract

    The levels of enzymic and non enzymic antioxidants were determined in Ehrlich’s Lymphoma Ascite (ELA) transplanted Swiss albino mice treated with the protein fraction of Cynodon dactylon (Cdpf). ELA induced mice showed significant decrease in the level of enzymic antioxidants like catalase (73.43 to 55.03), superoxide dismutase (4.49 to2.47) and glutathione peroxidase (48.48 to 36.98) in units/mg protein and non enzymic antioxidant like vitamin A (7.18 to 3.25), vitamin E (8.55 to 3.18) in µg/g protein and reduced glutathione (2.38 to 1.65) in nmoles/g protein which indicated the production of free radicals in the liver. Administration of protein fraction to the ELA induced mice showed enhanced level of enzymic antioxidants (69.18, 4.11 and 49.39 units/mg protein) and non enzymic antioxidants (5.63, 5.20 µg/g protein and 3.43 nmoles/g protein) respectively which proved their protective action against the free radical damage caused by ELA tumor cells and maintains the normal function of the organ and confirmed their antioxidant activity.

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  • About the authors and Affiliations

    Author(s) Name:

    R.Santhi*, K.Kalaiselvi and S.Annapoorani

    Affiliation(s) Name:

    *Department of Biochemistry, Vivekanandha College of Arts and Sciences (W), Tiruchengode - 637 205

    *Corresponding author.
    R.Santhi
    Department of Biochemistry, Vivekanandha College of Arts
    and Sciences (W), Tiruchengode- 637 205

    Received on: 25-10-2009; Revised on: 16-11-2009; Accepted on:09-01-2010

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    Author:

    R.Santhi*, K.Kalaiselvi and S.Annapoorani
    Title:Antioxidant efficacy of Cynodon dactylon leaf protein against ela implanted swiss albino mice
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (February)
    Year:2010
    Page No: (228-230)

  • Experimental Methods Keywords

    Methodology:Antioxidant properties, ELA
    Research Materials:Cynodon dactylon

Keywords

Cynodon dactylon Antioxidant properties ELA Swiss albino mice

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