Journal: Journal of Pharmacy Research
Title: Antidiabetic activity of Capparis decidua Forsk Edgew.
Category: Pharmacology
Section: Research Article
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Abstract
Ethnopharmacological relevance: Capparis decidua (Forsk.) Edgew (Capparidaceae) is well known for curing a variety of ailments such as toothache, cough, asthma, intermittent fever and rheumatism.Aim of the study: The present study was to evaluate antidiabetic activity of aqueous & ethanolic extract of Capparis decidua stem in alloxan-induced diabetic rats.Materials and methods: Albino rats were rendered diabetic by alloxan (150 mg/kg, intraperitoneally). The aqueous & ethanolic extracts were orally administered to diabetic rats at 250 and 500 mg/kg doses daily for 21 days to determine antidiabetic activity. Results: The fasting blood glucose level decreases by 58.5, 83.6 % (aqueous extract) and 60.2, 98.51 (ethanolic extract) after 21st day in diabetic rats treated with a different doses of 250 mg and 500 mg/kg body weight respectively.Conclusion: In conclusion, the present study using biochemical assays pertaining to blood glucose level of different animal models reveals that aqueous and ethanolic extract of stem has significant hypoglycemic and antidiabetic potential.
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About the authors and Affiliations
Author(s) Name: S. Rathee*1, O. P. Mogla1, S. Sardana1, M. Vats1 & P. Rathee2
Affiliation(s) Name: 1Hindu College of Pharmacy, Sonepat
2PDM College of Pharmacy, Bahadurgarh*Corresponding author.
Sushila Rathee
Hindu College of Pharmacy, Sonepat, Hariyana, India
Received on: 20-09-2009; Revised on: 17-11-2009; Accepted on:08-01-2010-
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Author: S. Rathee*1, O. P. Mogla1, S. Sardana1, M. Vats1 & P. Rathee2
Title: Antidiabetic activity of Capparis decidua Forsk Edgew. Journal: Journal of Pharmacy Research Vol(issue): 3 (February) Year: 2010 Page No: (231-234) -
Experimental Methods Keywords
Methodology: antidiabetic activity Research Materials: Capparis decidua
Keywords
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