Article Id:JPRS-PCS-0000671 Title:Design, Evaluation, Parameters and Marketed Products of transdermal patches: A Review Category:Pharmaceutics Section:Review Article
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Abstract
Transdermal drug delivery system (TDDS) established itself as an integral part of novel drug delivery systems. In a broad sense, the term transdermal delivery system includes all topically administered drug formulations intended to deliver the active ingredient into the general circulation. Transdermal drug delivery systems are polymeric formulations which when applied to skin deliver the drug at a predetermined rate across dermis to achieve systemic effects. Transdermal dosage forms, though a costly alternative to conventional formulations, are becoming popular because of their unique advantages. Controlled absorption, more uniform plasma levels, improved bioavailability, reduced side effects, painless and simple application and flexibility of terminating drug administration by simply removing the patch from the skin are some of the potential advantages of transdermal drug delivery. Development of controlled release transdermal dosage form is a complex process involving extensive efforts. This review article describes the methods of preparation of different types of transdermal patches, evaluation parameters and some available marketed products.
Sakalle Parivesh1*, Dwivedi Sumeet2 and Dwivedi Abhishek3.
Affiliation(s) Name:
1 Lakshmi Narain College of Pharmacy, Bhopal, M.P. 2 Chordia Institute of Pharmacy, Indore, M.P. 3 NRI Institute of Pharmaceutical Sciences, Bhoapl, M.P.
*Corresponding author. Sakalle Parivesh Lakshmi Narain College of Pharmacy, Bhopal, M.P.
Received on: 20-10-2009; Revised on: 16-12-2009; Accepted on:07-01-2010