Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000693
Title: Fast dissolving Drug delivery system : Review Article
Category: Pharmaceutics
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    Swallowing a pill is a major difficulty encountered in case of geriatric and pediatric patient which leads to poor patient compliance due to unpalatable taste of drug. To troubleshoot these problems a new dosage form known as fast-dissolving tablet (FDT), has been developed which rapidly disintegrate and dissolve in saliva. FDT are intended and designed to disintegrate and dissolve in saliva and then easily swallowed without need of water which is a major benefit over conventional dosage form. These dosage forms are also used to attain instant a higher concentration of drug in body for immediate actions. Fast dissolving tablets can be prepared by various conventional methods like direct compression, wet granulation, moulding, spray drying, freeze drying, and sublimation. In 1986, the first lyophilized fast-dissolving technology Zydis® was introduced by Cardinal formerly R. P. Scherer and after that there was a continuous growth in names , technologies & patented technology by different companies. Now a number of fast-dissolving formulations are in market like Claritin Reditab (Manufacturer R.P.Scherr,Inc.), Risperdal M-Tab (Manufacturer Janseen pharmaceutics.), Tempra Quicklets (Manufacturer Cima Labs,inc) and the technology is still improving. Present review focuses on the need of FDTs, pros and cons, drugs/marketed preparations, manufacturing process involved, evaluation of products and future trend.

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    Author(s) Name:

    Sunita Kumari*, Sharad Visht, Pramod Kumar Sharma, Rakesh Kumar Yadav

    Affiliation(s) Name:

    Department of Pharmaceutical Technology,Meerut Institute of Engineering and Technology, Meerut, India.

    *Corresponding author.
    Sunita Kumari
    Department of Pharmaceutical Technology,
    Meerut Institute of Engineering and Technology, Meerut, India.


    Received on: 16-03-2010; Revised on: 15-04-2010; Accepted on:18-05-2010

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    Author:

    Sunita Kumari*, Sharad Visht, Pramod Kumar Sharma, Rakesh Kumar Yadav

    Title:Fast dissolving Drug delivery system : Review Article
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (June)
    Year:2010
    Page No: (1444-1449)
  • Experimental Methods Keywords

    Methodology:Fast dissolving Drug delivery system
    Research Materials:synthetic drugs

Keywords

Fast dissolving drug delivery system Marketed preparation of FDT Conventional techniques Patented technology Excipients used in FDDTs Evaluation of FDDTs.

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