Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000706
Title: Hypoglycemic activity of saraca indica Linn barks.
Category: Pharmacology
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    The present study was aimed to evaluate the hypoglycemic effect of the methanolic bark extracts of Saraca indica Linn in normal and streptozotocin induced diabetic rats. Saraca indica Linn belongs to the family Leguminosae is traditionally used for the treatment of menstrual disorders, piles, ulcers and many other disorders including diabetes. Diabetes was induced by a single dose intraperitoneal injection of 50mg/kg of streptozotocin in overnight fasted rats. The blood glucose levels of Streptozotocin induced diabetic rats were estimated on days 0th , 4th , 7th 10th and 15th after oral administration of the extract. In normal rats the blood glucose levels were estimated at 0th , 1st , 2nd , 3rd and 4th hours. In both of these models at 400mg/kg through oral route the extract has shown a very good hypoglycemic activity.

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    Author(s) Name:

    *1Preethi. F,Jennifer Fernandes, Pricilla. K

    Affiliation(s) Name:

    1Preethi Mol Francis, Nitte Gulabi Shetty Memorial Institute of Pharmaceutical Sciences,Paneer, Derlakatte, Mangalore,Karnataka, India.

    *Corresponding author.
    Preethi Mol Francis
    M.pharm. Part-II,Dept. of Pharmacology
    Nitte Gulabi Shetty Memorial Institute of Pharmaceutical Sciences,
    Paneer, Derlakatte, Mangalore


    Received on: 20-11-2009; Revised on: 16-12-2009; Accepted on:15-02-2010

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    Author:

    *1Preethi. F,Jennifer Fernandes, Pricilla. K

    Title:Hypoglycemic activity of saraca indica Linn barks.
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (March)
    Year:2010
    Page No: (491-493)
  • Experimental Methods Keywords

    Methodology:Hypoglycemic activity
    Research Materials:Saraca indica Linn

Keywords

Saraca indica Linn Hypoglycemic activity Normal rats Streptozotocin Glibenclamide.

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