Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-0000721
Title: Microwave assisted organic reaction as new tool in organic synthesis
Category: Pharmaceutical Chemistry
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  • Abstract

    Microwave assisted organic synthesis (MAOS) has emerged as a new “lead” in organic synthesis. The technique offers simple, clean, fast, efficient, and economic for the synthesis of a large number of organic molecules. In the recent year microwave assisted organic reaction has emerged as new tool in organic synthesis. Important advantage of this technology include highly accelerated rate of the reaction, Reduction in reaction time with an improvement in the yield and quality of the product. Now day’s technique is considered as an important approach toward green chemistry, because this technique is more environmentally friendly. This technology is still under-used in the laboratory and has the potential to have a large impact on the fields of screening, combinatorial chemistry, medicinal chemistry and drug development. Conventional method of organic synthesis usually need longer heating time, tedious apparatus setup, which result in higher cost of process and the excessive use of solvents/ reagents lead to environmental pollution. This growth of green chemistry holds significant potential for a reduction of the by product, a reduction in waste production and a lowering of the energy costs. Due to its ability to couple directly with the reaction molecule and by passing thermal conductivity leading to a rapid rise in the temperature, microwave irradiation has been used to improve many organic syntheses.

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  • About the authors and Affiliations

    Author(s) Name:

    A K Nagariya 2*, A K Meena 1, Kiran2, A K Yadav 2, U S Niranjan 2, A K Pathak2, B Singh 2 and M M Rao1

    Affiliation(s) Name:

    1National Institute of Ayurvedic Pharmaceutical Research, Patiala – 147001, Punjab, (India)
    2 School of pharmaceutical sciences, Shobhit University, Meerut, U.P. (India)

    *Corresponding author.
    A K Nagariya
    School of pharmaceutical sciences, Shobhit University,
    Meerut, U.P. (India)


    Received on: 20-10-2009; Revised on: 16-12-2009; Accepted on:25-02-2010

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    Author:

    A K Nagariya 2*, A K Meena 1, Kiran2, A K Yadav 2, U S Niranjan 2, A K Pathak2, B Singh 2 and M M Rao1

    Title:Microwave assisted organic reaction as new tool in organic synthesis
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (March)
    Year:2010
    Page No: (575-580)
  • Experimental Methods Keywords

    Methodology:Microwave assisted organic synthesis
    Research Materials:organic synthesis

Keywords

Microwave irradiation; MAOS; Green Chemistry; Yield Lead Reduction.

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