Journal: Journal of Pharmacy Research

Article Id: JPRS-MB-0000731
Title: In vitro antibacterial activity of essential oils of selected herbals against isolates from HIV/AIDS patients
Category: Microbiology
Section: Research Article
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    Opportunistic infections are common and in the cases of HIV/ AIDS, they are very harmful. Bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa,Shigella dysenteriae, and Proteus mirabilis isolated from HIV positive patients were tested for their sensitivity to essential oils from Cymbopogon citratus, Cymbopogon martinii, Cinnamomum zeylanicum, Rosmarinus officinalis, Mentha piperita, Pelarogonium graveolens, and Vitex negundo. In agar well diffusion method the selected essential oils were effective against both gram positive as well as gram negative organisms. For e.g, C. citratus was highly active against S.pneumoniae and least against S. aureus. C. martinii was highly active against S.typhi and least against .S. aureus. C.zeylanicum was highly active against S.pneumoniae and least against P.mirabilis. R..officinalis was highly active against P.mirabilis and least against P.aeruginosa. The minimal inhibitory concentration (MIC) of essential oil of C.zeylanicum against all test organisms was best (0.25 mg/ml) and it was quite comparable with the reference drug Chloramphenicol (0.25 mg/ml). The results for all other essential oils were moderate, when compared with the reference drug. The results for minimal bactericidal concentration (MBC) were similar to minimal inhibitory concentration results. As no organism was found to be resistant to the tested essential oil, the results indicated that those essential oils could be used (aromatherapy) in different forms for the prevention, control and treatment of opportunistic bacterial infections caused by those organisms, particularly in HIV/ AIDS cases.

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    Author(s) Name:

    P.Sivamani1*, A.S.Sahul Hameed1

    Affiliation(s) Name:

    1Aquaculture Biotechnology Division, C.Abdul Hakeem College, Melvisharam- 632 509, Vellore-Dt, T.N. India.

    *Corresponding author.
    P.Sivamani M.Sc., M.Phil.,
    Aquaculture Biotechnology Division,
    C.Abdul Hakeem College,Melvisharam, 632 509.
    Tamilnadu .India

    Received on: 20-11-2009; Revised on: 16-01-2010; Accepted on:15-02-2010

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    Author:

    P.Sivamani1*, A.S.Sahul Hameed1

    Title:In vitro antibacterial activity of essential oils of selected herbals against isolates from HIV/AIDS patients
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (March)
    Year:2010
    Page No: (672-678)
  • Experimental Methods Keywords

    Methodology:Antibacterial activity,HIV/AIDS patients
    Research Materials:Essential oils from Cymbopogon citratus, Cymbopogon martinii, Cinnamomum zeylanicum, Rosmarinus officinalis, Mentha piperita, Pelarogonium graveolens, and Vitex negundo

Keywords

Antibacterial activity opportunistic bacteria essential oils aromatherapy HIV and AIDS

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