Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000735
Title: Ethosomes: A novel tool for drug delivery through the skin
Category: Pharmaceutics
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  • Abstract

    Ethosomes are the ethanolic phospholipid vesicles which are used mainly for transdermal delivery of drugs. Ethosomes have higher penetration rate through the skin as compared to liposomes hence these can be used widely in place of liposomes. The increased permeation of ethosomes is probably due to its ethanolic content. Ethanol increases the cell membrane lipid fluidity which results in increased skin penetrability of the ethosomes. These ethosomes permeates inside the skin and fuse with cell membrane lipids and release the drug. Hot and cold methods are used for formulation of ethosomes. Evaluation parameters include size, shape, drug content, zeta potential etc. Ethosomes have been successfully evaluated for the delivery of many drugs for e.g. Cyclosporine A, insulin, salbutamol etc. Ethosomes can be important drug delivery tool in the future.

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    Author(s) Name:

    Gangwar Satyam*, Singh Shivani, Garg Garima

    Affiliation(s) Name:

    *Department of Pharmaceutical Technology,Meerut Institute of Engineering and Technology, NH-58, Baghpat Byepass Road,Meerut -250005(U.P.) India

    *Corresponding author.
    Gangwar Satyam
    Department of Pharmaceutical Technology,Meerut Institute of Engineering and Technology
    ,NH-58, Baghpat Byepass Road
    Meerut (U.P.) India – 250005


    Received on: 20-09-2009; Revised on: 16-12-2009; Accepted on:22-02-2010

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    Author:

    Gangwar Satyam*, Singh Shivani, Garg Garima

    Title:Ethosomes: A novel tool for drug delivery through the skin
    Journal:Journal of Pharmacy Research
    Vol(issue):3(4)
    Year:2010
    Page No: (688-691)
  • Experimental Methods Keywords

    Methodology:drug delivery through the skin
    Research Materials:Ethosomes

Keywords

Ethosomes transdermal skin permeation vesicles

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