Journal: Journal of Pharmacy Research

Article Id: JPRS-MB-0000760
Title: Cow Urine Concentrate : A potent agent with Antimicrobial and Anthelmintic activity
Category: Microbiology
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    Cow, often called Kamadhenu, has been considered as a sacred animal in India. The present study was undertaken to determine antibacterial, antifungal and anthelmintic activity of Cow urine concentrate (CUC) which is obtained by complete evaporation of cow urine. The antibacterial activity was tested against Gram positive and Gram negative bacteria by disc diffusion method. Antifungal activity was tested against species of Aspergillus by Agar well diffusion method. Anthelmintic activity was studied using adult Indian earthworm model. Marked inhibition of Gram positive bacteria was observed by the CUC. Inhibition of fungi was found to be dose dependent. Among fungi tested, A. niger was more affected than others. In anthelmintic assay, concentration dependent mortality of worms was observed and the effect by CUC was found to be more superior as compared to the standard drug Piperazine citrate. The antimicrobial and anthelmintic activity of CUC may be due to the presence of constituents present in it. The CUC could be used in the treatment of diseases caused by pathogenic bacteria, opportunistic fungi and parasitic helminthes. Further studies on isolation of inhibitory components and in vivo experiments are to be carried out.

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    Author(s) Name:

    Prashith Kekuda T.R 1*, Nishanth B.C 2, Praveen Kumar S.V 3, Kamal D 1, Sandeep M 4, Megharaj H.K 1

    Affiliation(s) Name:

    1 Dept. of Microbiology, S.R.N.M.N College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India
    2 Dept. of Studies and Research in Biochemistry, Kuvempu University, Jnanasahyadri, Shankaraghatta-577451, Karnataka, India
    3 Dept. of Studies and Research in Microbiology, Kuvempu University, Shivagangothri, Tholhunse, Davangere-577002, Karnataka, India
    4 Dept. of Studies and Research in Applied Geology, Kuvempu University, Jnanasahyadri, Shankaraghatta-577451, Karnataka, India

    *Corresponding author.
    Prashith Kekuda T.R
    Department of Microbiology, S.R.N.M.N College of Applied Sciences,
    NES Campus, Balraj Urs Road, Shivamogga-577201,
    Karnataka, INDIA


    Received on: 21-01-2010; Revised on: 12-03-2010; Accepted on:14-04-2010

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    Author:

    Prashith Kekuda T.R 1*, Nishanth B.C 2, Praveen Kumar S.V 3, Kamal D 1, Sandeep M 4, Megharaj H.K 1

    Title:Cow Urine Concentrate : A potent agent with Antimicrobial and Anthelmintic activity
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (May)
    Year:2010
    Page No: (1025-1027)
  • Experimental Methods Keywords

    Methodology:Antimicrobial and Anthelmintic activity
    Research Materials:Cow urine concentrate

Keywords

Cow urine concentrate Antimicrobial activity Anthelmintic activity Disc diffusion method Agar well diffusion method Zone of inhibition.

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