Journal: Journal of Pharmacy Research

Article Id: JPRS-PB-0000763
Title: Investigations on purification ,characterization and antimicrobial activity of enzyme papain from Carica papaya Linn.
Category: Pharmaceutical Biotechnology
Section: Research Article
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    The proteolytic enzyme papain was extracted from the latex of the fruit Carica papaya Linn. in a highly purified manner, where the extracted enzyme has been characterized to determine its efficiency and its molecular weight is found to be 23,000 daltons to 25,000 daltons from the bands obtained. Papain showed more significant activity against bacteria than fungi. The zone of inhibition of papain against Pseudomonas aerogenosa, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus was 25, 22, 24 and 18mm where as for fungal clinical isolates Candida albicans was 18 mm. From this study, we conclude that papain has good therapeutic property and can be used as potential drug for bacterial and fungal diseases.

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    Author(s) Name:

    *1Seenivasan. R, 1Roopa.L and 2Geetha.S

    Affiliation(s) Name:

    1Division of Environmental Biotechnology, School of Bio sciences and Technology (SBST), VIT University, Vellore-632 014, Tamil Nadu,India.
    2Department of Plant Biology and Biotechnology,Arignar Anna Govt.Arts College for Women, Walajapet-632 513 Tamil Nadu, India.

    *Corresponding author.
    Seenivasan. R
    1Division of Environmental Biotechnology, School of Bio sciences and Technology (SBST), VIT University, Vellore-632 014, Tamil Nadu,India.


    Received on: 10-01-2010; Revised on: 16-03-2010; Accepted on:14-04-2010

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    Author:

    *1Seenivasan. R, 1Roopa.L and 2Geetha.S

    Title:Investigations on purification ,characterization and antimicrobial activity of enzyme papain from Carica papaya Linn.
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (May)
    Year:2010
    Page No: (1092-1095)
  • Experimental Methods Keywords

    Methodology:antibacterial activity, antifungal activity
    Research Materials:Carica papaya Linn.

Keywords

Papain antibacterial activity antifungal activity

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