Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-0000764
Title: Anti-inflammatory and analgesic activities of Tephrosia purpurea Linn. aerial and root extracts
Category: Pharmaceutical Chemistry
Section: Research Article
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  • Abstract

    An ethanolic extract of the aerial (EETPA) and root parts of Tephrosia purpurea Linn. (EETPR) was investigated for anti-inflammatory and analgesic activities. The extract (250, 500 mg/kg, b.w) produced dose-related inhibition of carrageenan-induced paw edema and cotton pellet-induced granuloma in rats. At the same doses, analgesic activity was also observed by tail immersion method maintained at 55°C. The results of the present study further confirms that the use of Tephrosia purpurea Linn. Traditionally used for the treatment of painful inflammatory pathological conditions like fracture and dislocation.

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    Author(s) Name:

    Gopalakrishnan S*, Vadivel E and Dhanalakshmi K

    Affiliation(s) Name:

    Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli -627 012, India.

    *Corresponding author.
    Gopalakrishnan S
    Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli-627 012, India.


    Received on: 15-01-2010; Revised on: 19-02-2010; Accepted on:11-04-2010

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    Author:

    Gopalakrishnan S*, Vadivel E and Dhanalakshmi K

    Title:Anti-inflammatory and analgesic activities of Tephrosia purpurea Linn. aerial and root extracts
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (May)
    Year:2010
    Page No: (1103-1106)
  • Experimental Methods Keywords

    Methodology: Anti-inflammatory; carrageenan induced paw, cotton pellet granulama; edema method; tail-immersion method,
    Research Materials:Tephrosia purpurea

Keywords

Anti-inflammatory; carrageenan induced paw cotton pellet granulama; edema method; tail-immersion method Tephrosia purpurea

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