Journal: Drug Invention Today

Article Id: JPRS-PS-0000859
Title: Free radical scavenging and insecticidal activity of Elaeagnus kologa Schldl.
Category: Pharmacological Screening
Section: Research Article
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    Free radicals contribute to more than one hundred disorders in humans. Mosquitoes are the most important single group of insects acting as vector for many tropical and subtropical diseases. The present study was conducted to screen various solvent extracts of Elaeagnus kologa Schldl. for Antioxidant activity by DPPH radical scavenging assay and insecticidal activity against second instar larvae of Aedes aegypti. The extracts have exhibited concentration dependent radical scavenging activity. Among the extracts, methanol extract exhibited high free radical scavenging activity. A concentration dependent larval mortality was observed in all the extracts. The larval mortality was recorded as 100% in the case of 15 and 20mg/ml of methanol, ethyl acetate and acetone extracts. The radical scavenging and insecticidal activity could be attributed to the presence of phytochemicals in the solvent extracts.

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    Author(s) Name:

    K.S. Vinayaka*1, T.R. Prashith Kekuda 2, H.R. Nethravathi 3, N.B. Thippeswamy 3, S.J. Sudharshan2

    Affiliation(s) Name:

    1 Dept. of Studies and Research in Applied Botany, Jnanasahyadri, Shankaraghatta-577451, Karnataka, India
    2 Dept. of Microbiology, S.R.N.M.N College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India
    3 Dept. of Studies and Research in Microbiology, Jnanasahyadri, Shankaraghatta-577451, Karnataka. India

    *Corresponding author.
    K.S. Vinayaka
    Dept. of Studies and Research in Applied Botany,
    Jnanasahyadri, Shankaraghatta-577451,
    Karnataka, India


    Received on: 15-07-2009; Revised on: 21-08- 2009; Accepted on:05-10-2009

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    Author:

    K.S. Vinayaka*1, T.R. Prashith Kekuda 2, H.R. Nethravathi 3, N.B. Thippeswamy 3, S.J. Sudharshan2

    Title:Free radical scavenging and insecticidal activity of Elaeagnus kologa Schldl.
    Journal:Drug Invention Today
    Vol(issue):1 (January 2009)
    Year:2009
    Page No: (74-77)
  • Experimental Methods Keywords

    Methodology:Soxhlet extraction, DPPH assay, Insecticidal activity
    Research Materials:Elaeagnus kologa Schldl.

Keywords

Elaeagnus kologa Schldl. Soxhlet extraction DPPH assay Insecticidal activity Aedes aegypti

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