Journal: Drug Invention Today

Article Id: JPRS-PS-0000860
Title: Studies on diuretic and laxative activity of bark extracts of Neolamarckia cadamba (Roxb.) Bosser
Category: Pharmacological Screening
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    The diuretic and laxative activity of various extracts of the barks of Neolamarckia cadamba (Roxb.) Bosser (Family: Rubiaceae) were studied in Wistar albino rats. Furosemide (10 mg/kg, p.o.) and agar-agar (300 mg/kg, p.o.) were used as reference standards respectively for activity comparison. The methanol extract significantly increased the urinary out put as well as urinary electrolyte concentration at the tested dosage regimen that is comparable with the reference standard except in increasing the urinary out put. The chloroform extract produced significant laxative activity. Presence of different phytoconstituents in various extracts of N. cadamba may be responsible for the specific activities.

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    Author(s) Name:

    Mondal S1*, Dash G. K1, Acharyya A1 , Acharyya S1 and Sharma H.P2

    Affiliation(s) Name:

    1Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot district, Gujarat -360 440.
    2Sri Balaji College of Pharmacy, Jaipur, Rajasthan – 302 013.

    *Corresponding author.
    Mondal S
    Matushree V. B. Manvar College of Pharmacy,
    Dumiyani, Rajkot district,
    Gujarat -360 440.India


    Received on: 22-07-2009; Revised on:01-08- 2009; Accepted on:15-10-2009

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    Author:

    Mondal S1*, Dash G. K1, Acharyya A1 , Acharyya S1 and Sharma H.P2

    Title:Studies on diuretic and laxative activity of bark extracts of Neolamarckia cadamba (Roxb.) Bosser
    Journal:Drug Invention Today
    Vol(issue):1(1)
    Year:2009
    Page No: (78-80)
  • Experimental Methods Keywords

    Methodology:diuretic and laxative activity
    Research Materials:Neolamarckia cadamba.

Keywords

Acute toxicity diuretic laxative Neolamarckia cadamba.

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