Journal: Drug Invention Today

Article Id: JPRS-PS-0000863
Title: Anti-hyperglycemic activity of methanolic extract of Salacia fruticosa leaves in alloxan induced diabetic rats
Category: Pharmacological Screening
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    The aim of the present study was to evaluate the anti hyperglycemic activity of methanolic extract of leaves of Salacia fruticosa (Family:Hippocrataceae) in alloxan induced diabetic rats. The hyperglycemic rats were divided into different groups and were treated with methanolic extract of S. fruticosa at a dose of 125 & 250mg/kg. Treatment with extract produced a significant dose dependent reduction in blood glucose levels and this anti hyperglycemic activity was comparable with the reference standard, metformin. The results of the present study revealed the anti-diabetic activity of methanolic extract of leaves of Salacia fruticosa in alloxan induced diabetic rats.

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    Author(s) Name:

    E. Venkateshwarlu1*, A. Rama Narsimha Reddy2, A. Shyam Sunder1, G. Kiran3, J. Venkateshwar Rao3 and S. Madhusudhan1

    Affiliation(s) Name:

    1 Department of Pharmacy practice, Annamalai University, Annamalainagar, Tamilnadu, India.
    2Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, India.
    3 Department of Pharmaceutical Chemistry, Talla Padmavathi College of Pharmacy, Warangal, India.

    *Corresponding author.
    Mr. A. Shyam Sunder
    Department of Pharmacology,
    S.R. College of Pharmacy,
    Ananthasagar, Hasanparthy, Warangal, India


    Received on: 25-05-2009; Revised on: 21-07- 2009; Accepted on:08-10-2009

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    Author:

    E. Venkateshwarlu1*, A. Rama Narsimha Reddy2, A. Shyam Sunder1, G. Kiran3, J. Venkateshwar Rao3 and S. Madhusudhan1

    Title:Anti-hyperglycemic activity of methanolic extract of Salacia fruticosa leaves in alloxan induced diabetic rats
    Journal:Drug Invention Today
    Vol(issue):1 (December)
    Year:2009
    Page No: (95-97)
  • Experimental Methods Keywords

    Methodology:Anti-hyperglycemic activity
    Research Materials:Salacia fruticosa

Keywords

Salacia fruticosa; diabetic; antihyperglycemic; alloxan

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