Journal: Drug Invention Today
Title: Anti-hyperglycemic activity of methanolic extract of Salacia fruticosa leaves in alloxan induced diabetic rats
Category: Pharmacological Screening
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
The aim of the present study was to evaluate the anti hyperglycemic activity of methanolic extract of leaves of Salacia fruticosa (Family:Hippocrataceae) in alloxan induced diabetic rats. The hyperglycemic rats were divided into different groups and were treated with methanolic extract of S. fruticosa at a dose of 125 & 250mg/kg. Treatment with extract produced a significant dose dependent reduction in blood glucose levels and this anti hyperglycemic activity was comparable with the reference standard, metformin. The results of the present study revealed the anti-diabetic activity of methanolic extract of leaves of Salacia fruticosa in alloxan induced diabetic rats.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: E. Venkateshwarlu1*, A. Rama Narsimha Reddy2, A. Shyam Sunder1, G. Kiran3, J. Venkateshwar Rao3 and S. Madhusudhan1
Affiliation(s) Name: 1 Department of Pharmacy practice, Annamalai University, Annamalainagar, Tamilnadu, India.
2Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, India.
3 Department of Pharmaceutical Chemistry, Talla Padmavathi College of Pharmacy, Warangal, India.*Corresponding author.
Mr. A. Shyam Sunder
Department of Pharmacology,
S.R. College of Pharmacy,
Ananthasagar, Hasanparthy, Warangal, India
Received on: 25-05-2009; Revised on: 21-07- 2009; Accepted on:08-10-2009-
View Article File in pdf format.
Article File
-
View Article Citation Here.
5 View More -
How to Cite my Article.
Author: E. Venkateshwarlu1*, A. Rama Narsimha Reddy2, A. Shyam Sunder1, G. Kiran3, J. Venkateshwar Rao3 and S. Madhusudhan1
Title: Anti-hyperglycemic activity of methanolic extract of Salacia fruticosa leaves in alloxan induced diabetic rats Journal: Drug Invention Today Vol(issue): 1 (December) Year: 2009 Page No: (95-97) -
Experimental Methods Keywords
Methodology: Anti-hyperglycemic activity Research Materials: Salacia fruticosa
Keywords
Our Services
- Evaluation of Cardioprotective Role of Vinpocetine in Isoproterenol-induced Myocardial Infarction in Rats
- Solubility and Dissolution Enhancement: An overview
- Ethosomes: A novel tool for drug delivery through the skin
- Antimicrobial activity and phytochemical screening of five wild plants against Escherichia coli, Bacillus subtilis and Staphylococcus aureus
- A review on quality by design approach for analytical method development
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Evaluation of Phenolic Content and Antioxidant Capacity of leaf extract from Phoenix Dactylifera L obtained by different pH of aqueous extraction
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Biological synthesis of silver nanoparticles using aqueous leaf extract of Capparis decidua (FORSK.) EDGEW: A better alternative
- Zinc-silibinin complex ameliorates oxidative stress in high fat fed low dose STZ induced type 2 diabetes in rats
- Study of health related quality of life in rheumatoid arthritis patients
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- In vitro antioxidant, anti-inflammatory and anticholinesterase activities of Rumex vesicarius L
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Gastroprotective effect of Fenugreek 4-hydroxyisoleucine and trigonelline enriched fraction (TF4H (28%)) Sugaheal® against indomethacin induced ulcer in male wistar rats.
- Prescribing Patterns of antihypertensive drugs in a South Indian tertiary care hospital
- In vitro anti-Candida activity of Calotropis gigantea.
- Melatonin affords protection against myocardial ischemia-induced cerebral mitochondrial dysfunction: an in vivo study.
- Anti ulcer activity of Naravelia zeylanica leaves extract
- Pharmacognostic, Phytochemical & Quantitative Investigation of Saraca asoca leaves
- Effects of Osmolytes on The Structural Stability of Bovine Trypsin: A Brief Review
- Synthesis and Biological Activity of Novel Acyl Hydrazone Derivatives of 3-(4,5-diphenyl-1,3-oxazol-2-yl) propanoic acid as Anticancer, Analgesic and Anti-inflammatory Agents
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Design and Synthesis of Novel Quinazolinone Derivatives as Broad Spectrum Anticonvulsant and Antimicrobial Agent
- In vitro Antioxidant Activity from Leaves of Oroxylum indicum (L.) Vent. -A North Indian Highly Threatened and Vulnerable Medicinal Plant
- Genome of Acinetobacter baumannii Carries Multi Drug Resistance Genes
- Triazole analogues as novel antioxidants: In vitro bioassay and molecular modeling studies
- Assessment of Pharmacognostical Characters of Leaves of Tephrosia Purpurea Linn
- Anticonvulsant And Antioxidant Actions Of Some Dibenzo-a-Pyrone Derivatives In Pentylene –Induced Kindling Model In Mice
- Phytochemical Screening and Evaluation of Polyphenols, Flavonoids and Antioxidant Activity of Prunus cerasoides D. Don Leaves