Journal: Drug Invention Today
Title: Anti-hyperglycemic activity of methanolic extract of Salacia fruticosa leaves in alloxan induced diabetic rats
Category: Pharmacological Screening
Section: Research Article
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Abstract
The aim of the present study was to evaluate the anti hyperglycemic activity of methanolic extract of leaves of Salacia fruticosa (Family:Hippocrataceae) in alloxan induced diabetic rats. The hyperglycemic rats were divided into different groups and were treated with methanolic extract of S. fruticosa at a dose of 125 & 250mg/kg. Treatment with extract produced a significant dose dependent reduction in blood glucose levels and this anti hyperglycemic activity was comparable with the reference standard, metformin. The results of the present study revealed the anti-diabetic activity of methanolic extract of leaves of Salacia fruticosa in alloxan induced diabetic rats.
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About the authors and Affiliations
Author(s) Name: E. Venkateshwarlu1*, A. Rama Narsimha Reddy2, A. Shyam Sunder1, G. Kiran3, J. Venkateshwar Rao3 and S. Madhusudhan1
Affiliation(s) Name: 1 Department of Pharmacy practice, Annamalai University, Annamalainagar, Tamilnadu, India.
2Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, India.
3 Department of Pharmaceutical Chemistry, Talla Padmavathi College of Pharmacy, Warangal, India.*Corresponding author.
Mr. A. Shyam Sunder
Department of Pharmacology,
S.R. College of Pharmacy,
Ananthasagar, Hasanparthy, Warangal, India
Received on: 25-05-2009; Revised on: 21-07- 2009; Accepted on:08-10-2009-
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Author: E. Venkateshwarlu1*, A. Rama Narsimha Reddy2, A. Shyam Sunder1, G. Kiran3, J. Venkateshwar Rao3 and S. Madhusudhan1
Title: Anti-hyperglycemic activity of methanolic extract of Salacia fruticosa leaves in alloxan induced diabetic rats Journal: Drug Invention Today Vol(issue): 1 (December) Year: 2009 Page No: (95-97) -
Experimental Methods Keywords
Methodology: Anti-hyperglycemic activity Research Materials: Salacia fruticosa
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