Journal: Drug Invention Today
Title: Analgesic, Antipyretic and Anti-inflammatory Effect of the Whole Plant Extract of Desmostachya bipinnata Stapf (Poaceae) in Albino Rats
Category: Pharmacological Screening
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Analgesic, Antipyretic and anti-inflammatory effect of petroleum ether, benzene chloroform, ethanol and aqueous extract of the whole parts of Desmostachya bipinnata Stapf (Poaceae) was investigated in albino rats. Animals were given a subcutaneous injection of 12% w/v suspension of yeast (1ml /100gm Body weight) suspended in 0.5% w/v methylcellulose solution which leads to pyrexia. Oral administration of petroleum ether, chloroform, ethanol and aqueous extract of the whole parts of Desmostachya bipinnata Stapf (Poaceae) at a dose 300 mg/ kg body weight into six groups of animal for both the activities were shown significantly reduce the elevated body temperature of rat which was compared with standard paracetamol (marketed product) and diclofenac sodium respectively. The anti-inflammatory activity was evaluated by using Digital plethysmometer. The study was carried out using dose of 300 mg/kg orally. All the extracts produced statistically significant and dose dependent inhibition of edema induced by carrageenan at all doses when compared to the control groups.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Somezeet Panda1*, N. S. K Choudhury 2, V. Jagannath Patro3, Dipti Kanta Pradhan, Goutam Kumar Jana1
Affiliation(s) Name: *1Department of Pharmacy, Gayatri College of Pharmacy, Jamadarpali, Sason, Sambalpur, Orissa, 768200,India
2 Pharmacy Wing, SCB Medical College, Cuttack, Orissa, India
3 Department of Pharmachemistry,College of Pharmaceutical Sciences, Mohuda, Berhampur, Ganjam, Orissa, India*Corresponding author.
Mr. Somezeet Panda,
Department of Pharmacy,
Gayatri College of Pharmacy,
Jamadarpali, Sambalpur, Sason,
Orissa, 768200, India
Received on: 20-05-2009; Revised on: 21-06- 2009; Accepted on:15-07-2009-
View Article File in pdf format.
Article File
-
View Article Citation Here.
12 View More -
How to Cite my Article.
Author: Somezeet Panda1*, N. S. K Choudhury 2, V. Jagannath Patro3, Dipti Kanta Pradhan, Goutam Kumar Jana1
Title: Analgesic, Antipyretic and Anti-inflammatory Effect of the Whole Plant Extract of Desmostachya bipinnata Stapf (Poaceae) in Albino Rats Journal: Drug Invention Today Vol(issue): 1 (December) Year: 2009 Page No: (150-153) -
Experimental Methods Keywords
Methodology: Analgesic, Antipyretic and Anti-inflammatory Activity Research Materials: Desmostachya bipinnata Stapf
Keywords
Our Services
- Ashwini Shenai, Dhanraj Ganapathy*, Revathy Gounder
- Orally Disintegrating Tablets: A Review
- Application of nanotechnology for Ayurvedic drugs and formulations
- The effect of red betel leaves (Piper crocatum Ruiz and Pav.) on blood sugar and insulin expression levels in rat (Rattus norvegicus domesticus) models of diabetes mellitus
- Antimicrobial activity of ß-asarone from Acorus calamus leaves
- Phytosomes: a potential phyto-phospholipid carriers for herbal drug delivery
- Anatomical observation and morphometric analysis of impressions of dural venous sinuses in dry human occipital bone
- Effect of Kapalbhati Pranayama in the blood sugar level in diabetic patients
- Excessive usage of headphones among college students and their effects
- Knowledge, attitude, and awareness regarding needlestick injury among dental practitioners in Chennai
- Evaluation of skin corrosive property of ethanolic leaf extract of Acyranthus aspera by in vitro Transcutaneous Electrical Resistance Test and Human skin Model Test.
- Anti-pyretic activity of the ethanolic extract of the powdered leaves of Murraya Koenigii (L.) Spreng
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Effect of music on academic performance of college students
- Development and Evaluation of Polysaccharide Based Matrix Tablets of Celecoxib for Colonic Delivery
- Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation
- Characterization and formulation of prednisolone acetate reconstituted suspension
- Use of Canna indica Flower Extract As A Natural Indicator In Acid Base Titration
- Optimization of Irbesartan tablet formulation by 22 factorial design
- Evaluation of acute and subacute toxicity of aqueous extracts from Marrubium vulgare L in rodents
- Triazolo aspirins inhibit proliferation of C6 glioma cell lines in vitro
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Wound healing activity of the leaves of Tribulus terrestris (linn) aqueous extract in rats
- Insights into Polymers: Film Formers in Mouth Dissolving Films
- Abutment selection in fixed partial denture - A review
- Dose dependent antioxidant activity of fresh juice of leaves of Coriandrum sativum
- Abrus precatorius Linnaeus: A Phytopharmacological Review
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Simultaneous estimation of rizatriptan, sumatriptan and zolmitriptan by RP-HPLC method in bulk
- Docetaxel-loaded chitosan nanoparticles to enhance the chemotherapeutic efficacy in lung cancer