Journal: Drug Invention Today
Title: Analgesic, Antipyretic and Anti-inflammatory Effect of the Whole Plant Extract of Desmostachya bipinnata Stapf (Poaceae) in Albino Rats
Category: Pharmacological Screening
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Analgesic, Antipyretic and anti-inflammatory effect of petroleum ether, benzene chloroform, ethanol and aqueous extract of the whole parts of Desmostachya bipinnata Stapf (Poaceae) was investigated in albino rats. Animals were given a subcutaneous injection of 12% w/v suspension of yeast (1ml /100gm Body weight) suspended in 0.5% w/v methylcellulose solution which leads to pyrexia. Oral administration of petroleum ether, chloroform, ethanol and aqueous extract of the whole parts of Desmostachya bipinnata Stapf (Poaceae) at a dose 300 mg/ kg body weight into six groups of animal for both the activities were shown significantly reduce the elevated body temperature of rat which was compared with standard paracetamol (marketed product) and diclofenac sodium respectively. The anti-inflammatory activity was evaluated by using Digital plethysmometer. The study was carried out using dose of 300 mg/kg orally. All the extracts produced statistically significant and dose dependent inhibition of edema induced by carrageenan at all doses when compared to the control groups.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Somezeet Panda1*, N. S. K Choudhury 2, V. Jagannath Patro3, Dipti Kanta Pradhan, Goutam Kumar Jana1
Affiliation(s) Name: *1Department of Pharmacy, Gayatri College of Pharmacy, Jamadarpali, Sason, Sambalpur, Orissa, 768200,India
2 Pharmacy Wing, SCB Medical College, Cuttack, Orissa, India
3 Department of Pharmachemistry,College of Pharmaceutical Sciences, Mohuda, Berhampur, Ganjam, Orissa, India*Corresponding author.
Mr. Somezeet Panda,
Department of Pharmacy,
Gayatri College of Pharmacy,
Jamadarpali, Sambalpur, Sason,
Orissa, 768200, India
Received on: 20-05-2009; Revised on: 21-06- 2009; Accepted on:15-07-2009-
View Article File in pdf format.
Article File
-
View Article Citation Here.
12 View More -
How to Cite my Article.
Author: Somezeet Panda1*, N. S. K Choudhury 2, V. Jagannath Patro3, Dipti Kanta Pradhan, Goutam Kumar Jana1
Title: Analgesic, Antipyretic and Anti-inflammatory Effect of the Whole Plant Extract of Desmostachya bipinnata Stapf (Poaceae) in Albino Rats Journal: Drug Invention Today Vol(issue): 1 (December) Year: 2009 Page No: (150-153) -
Experimental Methods Keywords
Methodology: Analgesic, Antipyretic and Anti-inflammatory Activity Research Materials: Desmostachya bipinnata Stapf
Keywords
Our Services
- Evaluation of pulmonary function test in construction workers
- Investigations on purification ,characterization and antimicrobial activity of enzyme papain from Carica papaya Linn.
- Antibacterial activity of different endodontic sealers: An in vitro evaluation
- Effectiveness of good behavior game on oral health among children - A randomized trial
- Effect of music on academic performance of college students
- Estimation of Tizanidine HCl by UV-Spectrophotometric Method
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Medicinal uses of banana (Musa paradisiaca)
- The role of toponymic objects in the system of settlement and reconstruction of landscapes in the Pre-Volga Region of the Republic of Tatarstan
- Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation
- Biodegradable plastic production from corn starch
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Effects of lupeol on insulin receptor and glucose transporter-4 in cardiac tissue of Type-2 diabetic rats
- Formulation and evaluation of solid dispersions of valsartan for dissolution rate enhancement
- Simultaneous Spectrophotometric Estimation of Paracetamol and Aceclofenac in Combined Tablet Formulations using Hydrotropic Solubilization Technique
- Aspergillus Derived Silver Nano Particles as a Potent Antibacterial Agent and Identification of Linked Proteins
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Formulation and Evaluation of Sildenafil Citrate Fast Dissolving Tablets Using Crospovidone and Croscarmellose Sodium Superdisintegrants
- Assortment of vital nutrients for enhancement of Cyclodextrin glycosyltransferase produced by Bacillus amyloliquefaciens KST5: A Plackett-Burman design approach
- Fomulation and Evaluation of Taste Masked Spherical Agglomerates of Telmisartan
- Comparative Study of Ionotropic Gelation Technique To Entrap Diltiazem HCl In Mucoadhesive Microparticulate System.
- Validation of Uv Spectrophotometric method for estimation of Levocetirizine Dihydrochloride in bulk and pharmaceutical formulation
- Novel Controlled Gastroretentive Drug Delivery Systems: A Review
- In vitro antibacterial activity of essential oils of selected herbals against isolates from HIV/AIDS patients
- Preparation and Characterization of Pharmaceutical Grade Chitosan And Hydrated Chitosan Gums for Topical Preparations
- Antiulcer activity of aqueous suspension of Saraca indica flower against gastric ulcers in albino rats
- In silico and in vivo approach to identify the antidiabetic activity of lupeol
- Ethosomes: A novel tool for drug delivery through the skin
- A Case Study on Zinc Phosphide Poisoning in Tamil Nadu