Journal: Drug Invention Today
Title: Analgesic, Antipyretic and Anti-inflammatory Effect of the Whole Plant Extract of Desmostachya bipinnata Stapf (Poaceae) in Albino Rats
Category: Pharmacological Screening
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Analgesic, Antipyretic and anti-inflammatory effect of petroleum ether, benzene chloroform, ethanol and aqueous extract of the whole parts of Desmostachya bipinnata Stapf (Poaceae) was investigated in albino rats. Animals were given a subcutaneous injection of 12% w/v suspension of yeast (1ml /100gm Body weight) suspended in 0.5% w/v methylcellulose solution which leads to pyrexia. Oral administration of petroleum ether, chloroform, ethanol and aqueous extract of the whole parts of Desmostachya bipinnata Stapf (Poaceae) at a dose 300 mg/ kg body weight into six groups of animal for both the activities were shown significantly reduce the elevated body temperature of rat which was compared with standard paracetamol (marketed product) and diclofenac sodium respectively. The anti-inflammatory activity was evaluated by using Digital plethysmometer. The study was carried out using dose of 300 mg/kg orally. All the extracts produced statistically significant and dose dependent inhibition of edema induced by carrageenan at all doses when compared to the control groups.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Somezeet Panda1*, N. S. K Choudhury 2, V. Jagannath Patro3, Dipti Kanta Pradhan, Goutam Kumar Jana1
Affiliation(s) Name: *1Department of Pharmacy, Gayatri College of Pharmacy, Jamadarpali, Sason, Sambalpur, Orissa, 768200,India
2 Pharmacy Wing, SCB Medical College, Cuttack, Orissa, India
3 Department of Pharmachemistry,College of Pharmaceutical Sciences, Mohuda, Berhampur, Ganjam, Orissa, India*Corresponding author.
Mr. Somezeet Panda,
Department of Pharmacy,
Gayatri College of Pharmacy,
Jamadarpali, Sambalpur, Sason,
Orissa, 768200, India
Received on: 20-05-2009; Revised on: 21-06- 2009; Accepted on:15-07-2009-
View Article File in pdf format.
Article File
-
View Article Citation Here.
12 View More -
How to Cite my Article.
Author: Somezeet Panda1*, N. S. K Choudhury 2, V. Jagannath Patro3, Dipti Kanta Pradhan, Goutam Kumar Jana1
Title: Analgesic, Antipyretic and Anti-inflammatory Effect of the Whole Plant Extract of Desmostachya bipinnata Stapf (Poaceae) in Albino Rats Journal: Drug Invention Today Vol(issue): 1 (December) Year: 2009 Page No: (150-153) -
Experimental Methods Keywords
Methodology: Analgesic, Antipyretic and Anti-inflammatory Activity Research Materials: Desmostachya bipinnata Stapf
Keywords
Our Services
- Evaluation of Cardioprotective Role of Vinpocetine in Isoproterenol-induced Myocardial Infarction in Rats
- In vitro antioxidant and ptp inhibitory activity of methanolic extract of Anogeissus acuminata leaf and bark.
- Ethosomes: A novel tool for drug delivery through the skin
- A review on Calotropis procera Linn and its Ethnobotany, Phytochemical, Pharmacological profile
- Antimicrobial activity and phytochemical screening of five wild plants against Escherichia coli, Bacillus subtilis and Staphylococcus aureus
- A review on quality by design approach for analytical method development
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Evaluation of Phenolic Content and Antioxidant Capacity of leaf extract from Phoenix Dactylifera L obtained by different pH of aqueous extraction
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Zinc-silibinin complex ameliorates oxidative stress in high fat fed low dose STZ induced type 2 diabetes in rats
- Biological synthesis of silver nanoparticles using aqueous leaf extract of Capparis decidua (FORSK.) EDGEW: A better alternative
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Prescribing Patterns of antihypertensive drugs in a South Indian tertiary care hospital
- Study of health related quality of life in rheumatoid arthritis patients
- In vitro antioxidant, anti-inflammatory and anticholinesterase activities of Rumex vesicarius L
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Gastroprotective effect of Fenugreek 4-hydroxyisoleucine and trigonelline enriched fraction (TF4H (28%)) Sugaheal® against indomethacin induced ulcer in male wistar rats.
- In vitro anti-Candida activity of Calotropis gigantea.
- Pharmacognostic, Phytochemical & Quantitative Investigation of Saraca asoca leaves
- Anti ulcer activity of Naravelia zeylanica leaves extract
- Melatonin affords protection against myocardial ischemia-induced cerebral mitochondrial dysfunction: an in vivo study.
- Effects of Osmolytes on The Structural Stability of Bovine Trypsin: A Brief Review
- Synthesis and Biological Activity of Novel Acyl Hydrazone Derivatives of 3-(4,5-diphenyl-1,3-oxazol-2-yl) propanoic acid as Anticancer, Analgesic and Anti-inflammatory Agents
- Design and Synthesis of Novel Quinazolinone Derivatives as Broad Spectrum Anticonvulsant and Antimicrobial Agent
- In vitro Antioxidant Activity from Leaves of Oroxylum indicum (L.) Vent. -A North Indian Highly Threatened and Vulnerable Medicinal Plant
- Assessment of Pharmacognostical Characters of Leaves of Tephrosia Purpurea Linn
- Genome of Acinetobacter baumannii Carries Multi Drug Resistance Genes
- Triazole analogues as novel antioxidants: In vitro bioassay and molecular modeling studies
- Anticonvulsant And Antioxidant Actions Of Some Dibenzo-a-Pyrone Derivatives In Pentylene –Induced Kindling Model In Mice