Journal: Drug Invention Today
Article Id: JPRS-DFA-0000871
Title: RP-HPLC method for the estimation of tamsulosin hydrochloride in bulk and tablet dosage form
Category: Drug or Formulation Analysis
Title: RP-HPLC method for the estimation of tamsulosin hydrochloride in bulk and tablet dosage form
Category: Drug or Formulation Analysis
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Abstract
The Present work describes a simple reverse phase HPLC method for the estimation of Tamsulosin hydrochloride in bulk and tablet dosage form. The estimation was carried out on ODS,Phenomonex,C-18 (250x4.6 mm,5μ) column using a mobile phase consisting of sodium dihydrogen orthophosphate buffer-Acetonitrile (70:30).The eluent was monitored at 280 nm. The results have been validated statistically and recovery studies confirmed the accuracy of proposed method.
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About the authors and Affiliations
Author(s) Name: T.S.Nithiyananthan*,V.Shankarananth1, K.K.Rajasekhar1, P.Ravikiran1, E.Vikram kumar1 and G.Jayanth kumar reddy1
Affiliation(s) Name: *,1-Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati-517503,Andhra Pradesh,India.
*Corresponding author.
T.S Nithiyanantham,
Department of Pharmaceutics,
Sri Padmavathi School of pharmacy,
Tiruchanoor,Tirupathi.
Andhra Pradesh, India.
Received on: 20-05-2009; Revised on: 21-06- 2009; Accepted on:15-07-2009-
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Author: T.S.Nithiyananthan*,V.Shankarananth1, K.K.Rajasekhar1, P.Ravikiran1, E.Vikram kumar1 and G.Jayanth kumar reddy1
Title: RP-HPLC method for the estimation of tamsulosin hydrochloride in bulk and tablet dosage form Journal: Drug Invention Today Vol(issue): 1 (December) Year: 2009 Page No: (154-156) -
Experimental Methods Keywords
Methodology: HPLC estimation Research Materials: Tamsulosin hydrochloride and Pharmaceutical formulation.
Keywords
HPLC estimation
Validation
Tamsulosin hydrochloride and Pharmaceutical formulation.
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