Journal: Drug Invention Today

Article Id: JPRS-D(DD)-0000875
Title: Orally Disintegrating Tablets: A Review
Category: Drug (Discovery/Development)
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    Over a decade, the demand for development of orally disintegrating tablets (ODTs) has enormously increased as it has significant impact on the patient compliance. Orally disintegrating tablets offer an advantage for populations who have difficulty in swallowing. Prescription ODT products initially were developed to overcome the difficulty in swallowing conventional tablets with water among pediatric, geriatric, and psychiatric patients with dysphagia. Today, ODTs are more widely available as over-the-counter products for the treatment of allergies and cold and flu symptoms. Technologies used for manufacturing of orally disintegrating tablets are either conventional technologies or patented technologies. In conventional freeze drying, tablet molding, sublimation, spray drying etc. and in patented Zydis technology, Orasolv technology, Durasolv technology, Wowtab technology, Flashdose technology are important. Important ingredients that are used in the formulation of ODTs should allow quick release of the drug, resulting in faster dissolution. Evaluation of these tablets are done by following weight variation, friability, tensile strength, wetting time, water absorption ratio, In vitro dispersion time and dissolution test.

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    Author(s) Name:

    Sudhir Bharawaj*, Vinay Jain, Shailesh Sharma, R. C. Jat and Suman Jain

    Affiliation(s) Name:

    *Pharmaceutics and Dosage Form Development Research Laboratory, Department of Pharmaceutics, Shriram College of Pharmacy,Banmore, Morena (M.P.) (INDIA)

    *Corresponding author.
    Dr.Sudhir Bharawaj
    Dean and Asst.Professor
    Pharmaceutics Research Laboratory,
    Department Of Pharmaceutics,
    Shriram College of Pharmacy,
    Banmore, Morena, (M.P.),India


    Received on: 10-06-2009; Revised on: 21-08- 2009; Accepted on:25-12-2009

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    Author:

    Sudhir Bharawaj*, Vinay Jain, Shailesh Sharma, R. C. Jat and Suman Jain

    Title:Orally Disintegrating Tablets: A Review
    Journal:Drug Invention Today
    Vol(issue):2 (January)
    Year:2010
    Page No: (81-88)
  • Experimental Methods Keywords

    Methodology: tensile strength, sublimation
    Research Materials:Orally disintegrating tablets

Keywords

Orally disintegrating tablets Orasolv tensile strength sublimation

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