Journal: Drug Invention Today

Article Id: JPRS-D(DD)-0000896
Title: Antibacterial study of silver doped zinc oxide nanoparticles against Staphylococcus aureus and Bacillus subtilis
Category: Drug (Discovery/Development)
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    Objectives

    The present study has been undertaken to synthesize silver doped zinc oxide nanoparticles, with pharmaceutical importance. The synthesized particles have been evaluated to study the effect of silver doping on grain size and further on antibacterial activities against the microorganismsBacillus subtilis and Staphylococcus aureus.

    Methods

    Silver doped zinc oxide nanoparticles were prepared by the solution route spin-coating process, using zinc acetate (Zn(CH3COO)2.2H2O) and silver nitrate (AgNO3) as host and dopant precursors respectively. The antibacterial activity of the silver doped zinc oxide were studied against S. auerus and B. subtilis via using agar well diffusion method.

    Results & discussion

    : The structure of the powder samples was analyzed by X-ray diffraction (XRD). The effect of silver doping on grain size and further on antibacterial activity against the microorganisms B. subtilis and S. auerus is discussed.

    Conclusion

    It was clear from X-ray investigations that its structure is wurtzite type and that an increase in Ag-doping resulted in decrease in the grain size of the ZnO nanoparticles. Antimicrobial study against the microorganisms B. subtilis and S. auerus shows that in case of S. auerus the MIC varies with increase in Ag content but in case of B. subtilis the MIC remained constant for all concentration of Ag.

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  • About the authors and Affiliations

    Author(s) Name:

    Neha Sharma a , Jitender Kumar a, *, Shaveta Thakur a , Shruti Sharma a , Vikas Shrivastava b

    Affiliation(s) Name:

    a Department of Physics, Arni University, Kangra, Himachal Pradesh 176401, India b Department of Biotechnology, Arni University, Kangra, Himachal Pradesh 176401, India

    Article history: Received 2 March 2013 Accepted 14 March 2013

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    Author:

    Neha Sharma a , Jitender Kumar a, *, Shaveta Thakur a , Shruti Sharma a , Vikas Shrivastava b

    Title:Antibacterial study of silver doped zinc oxide nanoparticles against Staphylococcus aureus and Bacillus subtilis
    Journal:Drug Invention Today
    Vol(issue):5 (January)
    Year:2013
    Page No: (50-54)
  • Experimental Methods Keywords

    Methodology:Antibacterial activity
    Research Materials:ZnO nanoparticles

Keywords

ZnO nanoparticles Antibacterial activity Crystallite size Doping

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