Journal: Drug Invention Today

Article Id: JPRS-PS-0000907
Title: Evaluation of the Hypoglycemic, Hypolipidemic and Antioxidant Effects of Methanolic Extract of “Ata-Ofa” Polyherbal Tea (APolyherbal) in Alloxan-Induced Diabetic Rats
Category: Pharmacological Screening
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Methanolic extract of “Ata-Ofa Polyherbal tea” (A-Polyherbal) was evaluated for hypoglycemic, hypolipidemic and antioxidant effects in alloxan-induced diabetic rats. Compared to the untreated diabetic rats, administration of methanolic extract of A-Polyherbal at 50mg/kg dose for 7 days caused a statistically significant (P < 0.05) percentage reduction in fasting blood glucose level (55.43±3.50%), significantly boosted the activities of superoxide dismutases and catalases, HDLcholesterol, packed cell volume and hemoglobin, and significantly (P < 0.05) reduced the levels of thiobarbituric reactive substances (TBARS), total cholesterol, total bilirubin, conjugated bilirubin, in alloxan-induced diabetic rats. These results strongly demonstrate that “Ata-Ofa Polyherbal tea” (A-Polyherbal) has strong potential in the alleviation and management of diabetes and related complications, including hyperglycemia, oxidative stress, development of micro and macro vascular diabetic complications arising from elevated plasma lipids and decreased levels of antioxidant defense systems, as well as reduced erythrocyte survival rate.

  • Abstract Audio

    Click Here

  • About the authors and Affiliations

    Author(s) Name:

    Sunday E Atawodi*

    Affiliation(s) Name:

    Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria

    Corresponding Author:
    Sunday E Atawodi, Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria


    Received 27-06-2011; Accepted 24-10-2011

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    15 View More
  • How to Cite my Article.

    Author:

    Sunday E Atawodi*

    Title:Evaluation of the Hypoglycemic, Hypolipidemic and Antioxidant Effects of Methanolic Extract of “Ata-Ofa” Polyherbal Tea (APolyherbal) in Alloxan-Induced Diabetic Rats
    Journal:Drug Invention Today
    Vol(issue):3 (November)
    Year:2011
    Page No: (270-276)
  • Experimental Methods Keywords

    Methodology:Hypoglycemic effect; Antioxidant effect, Hypolipidemic effect; alloxandiabetes; anti-diabetic effect
    Research Materials:Ata-Ofa Polyherbal tea

Keywords

Ata-Ofa Polyherbal tea; A-Polyherbal; Hypoglycemic effect; Antioxidant effect Hypolipidemic effect; alloxandiabetes; anti-diabetic effect

Our Services

Most Downloaded List