Journal: Drug Invention Today

Article Id: JPRS-D(DD)-0000934
Title: Multiparticlate drug delivery systems : Pellet & pelletization technique
Category: Drug (Discovery/Development)
Section: Review Article
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    The present study aims at discussing the potential advantages of multiple unit dosage forms (pellets etc.) over the single unit dosage forms (Tablets).Review deals with the pellet and its ideal properties. The theory behind the pellet formation and its growth mechanism. There are various types of pelletization techniques like spheronization and extrusion, pelletization by layering, pelletization by solution layering & direct pelletization. The advantages, disadvantages & various applications of above mentioned techniques. Spheronization and extrusion, pelletization by layering are most widely used techniques. It also deals with novel mini tablet system and its processing for formulation. The different available marketed pellets and different excipients used in the pellet formulation are also discussed.

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    Author(s) Name:

    *1Rangasamy Manivannan,1Kugalur Ganesan Parthiban, 1Gummudavelly Sandeep, 2Ayyasamy Balasubramaniam and 2Natesan Senthilkumar

    Affiliation(s) Name:

    1Department of Pharmaceutics, JKK Munirajah Medical Research Foundation,College of Pharmacy, Namakkal (DT), Tamilnadu, India.
    2Department of Pharmaceutical chemistry, JKK Munirajah Medical Research Foundation, College of Pharmacy, Namakkal (DT), Tamilnadu, India.

    *Corresponding author.
    R.Manivannan
    Professor
    JkkMunirajah Medical Research Foundation,
    College of Pharmacy;Namakkal (DT), Tamilnadu,India


    Received on: 20-10-2009; Revised on: 21-12- 2009; Accepted on:15-02-2010

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    Author:

    *1Rangasamy Manivannan,1Kugalur Ganesan Parthiban, 1Gummudavelly Sandeep, 2Ayyasamy Balasubramaniam and 2Natesan Senthilkumar

    Title:Multiparticlate drug delivery systems : Pellet & pelletization technique
    Journal:Drug Invention Today
    Vol(issue):2 (May)
    Year:2010
    Page No: (233-237)
  • Experimental Methods Keywords

    Methodology:Multiparticlate drug delivery systems
    Research Materials:Pellets

Keywords

Pellets Multiple unit dosage forms Spheronization Extrusion & Modified release.

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