Journal: Journal of Pharmacy Research
Title: Simultaneous Spectrophotometric Estimation of Nimesulide and Paracetamol in Liquid Dosage Form
Category: Pharmaceutical Analysis
Section: Research Article
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Abstract
Two highly sensitive and accurate methods have been developed for the estimation of Nimesulide and Paracetamol in liquid dosage form. First method is the simultaneous equation method by selecting the wave length maxima of 295 nm and 246 nm for Nimesulide and Paracetamol respectively. Second method is the Q- absorbance ratio method by selecting the wave length maxima 295 nm for Nimesulide and 273 nm,the iso-bestic point.There was no interference of the excipients. The methods have been validated for linearity, accuracy and precision and found to be rapid, precise and economical.
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About the authors and Affiliations
Author(s) Name: Satyabrata sahu1*, Chhanda Charan Danta2
Affiliation(s) Name: Department of Medicinal and Analytical Chemistry, Dadhichi College of Pharmacy, Sundargram,Cuttack, Orissa
*Corresponding author.
Satyabrata Sahu
Department of Medicinal and Analytical Chemistry,
Dadhichi College of Pharmacy, Sundargram,
Cuttack, Orissa
Received on: 13-04-2010; Revised on: 12-05-2010; Accepted on:19-07-2010-
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Author: Satyabrata sahu1*, Chhanda Charan Danta2
Title: Simultaneous Spectrophotometric Estimation of Nimesulide and Paracetamol in Liquid Dosage Form Journal: Journal of Pharmacy Research Vol(issue): 3 (August) Year: 2010 Page No: (1973-1975) -
Experimental Methods Keywords
Methodology: Simultaneous Spectrophotometric Estimation, UV Spectrophotometry, Simultaneous equation method, Q-absorbance ratio method Research Materials: Nimesulide and Paracetamol
Keywords
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