Journal: Journal of Pharmacy Research

Article Id: JPRS-PA-000098
Title: Novel UV spectrophotometric method for estimation of Nelfinavir by derivative spectroscopy
Category: Pharmaceutical Analysis
Section: Research Article
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  • Abstract

    Two Simple, precise and economical UV methods have been developed and validated for the quantitative estimation of Nelfinavir in bulk and pharmaceutical dosage forms. Nelfinavir showed sharp peak at lmax 255 nm (Method A, zero order), showed sharp peak at 248 nm (Method B, first order). Methanol was used as solvent for all methods. Beer’s-Lamberts law was found to be obeyed in the concentration range of 5-40 μg/ml. The developed methods were statically validated according to international conference on harmonization guidelines and were found to be accurate and reproducible. Results of the analysis were validated statistically and by recovery studies

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  • About the authors and Affiliations

    Author(s) Name:

    Nangare Ajit1*, Hapse Sandip2

    Affiliation(s) Name:

    1Department of pharmaceutical chemistry, Padmashree Dr.Vittalrao Vikhe Patil College of Pharmacy, Ahmednagar, Maharashtra. 414111,India.
    2Department Of Quality Assurance Technique,Padmashree Dr.Vittalrao Vikhe Patil College of Pharmacy, Ahmednagar, Maharashtra. 414111,India.

     

    *Corresponding author.
    Prof. Nangare Ajit
    Department of pharmaceutical chemistry,

    Padmashree Dr.Vittalrao Vikhe Patil College of Pharmacy,

    Ahmednagar, Maharashtra. 414111,India.



    Received on:21-11-2013; Revised on: 08-12-2013; Accepted on:11-12-2013

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    Author:

    Nangare Ajit1*, Hapse Sandip2

    Title:Novel UV spectrophotometric method for estimation of Nelfinavir by derivative spectroscopy
    Journal:Journal of Pharmacy Research
    Vol(issue):8 (January )
    Year:2014
    Page No: (68-72)
  • Experimental Methods Keywords

    Methodology:UV spectrophotometric method
    Research Materials:Nelfinavir

Keywords

Nelfinavir Derivative spectroscopy

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