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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).
Scopus Indexed (link http://www.scimagojr.com/journalsearch.php?q=21100325431&tip=sid&clean=0) 

Journal Metrics for this Journal of Pharmacy Research (Source ID: 21100325431): 2015(SNIP) Source Normalized Impact Per Paper : 0.575; SCImago Journal Rank (SJR):0.787; Impact Per Publication : 0.789 CiteScore 2016: 0.93(Top level : Life Science)

Year SJR Cites per document Year Value
2014 0.607 Cites / Doc. (4 years) 2014 0.607
2015 0.787 Cites / Doc. (4 years) 2015 0.789
2016 0.926 Cites / Doc. (4 years) 2016 0.926
    Cites / Doc. (3 years) 2014 0.607
    Cites / Doc. (3 years) 2015 0.789
    Cites / Doc. (2 years) 2014 0.607
    Cites / Doc. (2 years) 2015 0.789
2016   Cites / Doc. (4 years) 2016 0.926
Cites Year Value
External Cites per document 2014 0.607
External Cites per document 2015 0.789
External Cites per document 2016 0.926
Cites per document 2014 0.607
Cites per document 2015 0.789
Cites per document 2016 0.926

Manuscripts Published

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-HM-00001918
Title: Aloe vera - Nature’s healer
Category: Herbal medicine
Section: Review Article
Country: India
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Aloe vera is a plant that belongs to “Xanthorrhoeacea” family. It is used in herbal medicine since 1st century AD. Clinical evaluations revealed that the pharmacologically active ingredient is present in the gel and leaves. More than the 300 varieties of A. vera exists exhibiting its unique property. The use of herbal products shows minimal side effect but highly effective treatment. Even though there are various advances in fields of medicine, oral infections are considered as a serious public health problem. A. vera is said to be as “Portable Nature’s First Aid Kit” and has also been used in dentistry for its beneficial properties in various conditions. This review summarizes the various therapeutic application and clinical uses of A. vera in dentistry. However, further research should be carried out to unfold the various potential uses of A. vera plant in dentistry.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-PP-00001919
Title: Evaluation of knowledge, attitude, and practice about usage along with awareness on first aid measures among secondary school and intermediate students
Category: Pharmacy practice
Section: Research Article
Country: India
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Objective: The main aim of the first aid is to save the life, prevent degradation of the situation and to promote the recovery. The adequate knowledge on first aid can promote the chances of survival of the injured person. This study was conducted to assess the knowledge, attitude, and practice of secondary school and intermediate students toward the first aid. Methods: It is a prospective study conducted in randomly selected secondary schools and intermediate colleges of Piler Mandal, Chittoor district, Andhra Pradesh, for a period of 3 months using a validated questionnaire which consists of 28 questions to assess their knowledge, attitude, and practice about first aid. All statistical analyses were performed using Microsoft Excel 2010 and GraphPad Prism 7.0 software. Results and Discussion: The goal of first aid is to preserve life, prevent further injury and promote recovery. Statistically significant difference was not found in the knowledge (P = 0.6204), attitude (P = 0.2351), and practice (P = 0.9508) among secondary school and intermediate students about first aid measures. Conclusion: The knowledge, attitude, and practice of secondary school and intermediate students on first aid were found to be adequate, but still, it is the responsibility of each and every school to provide training on first aid measures and also to have fire extinguisher in their school campus.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-GS-00001920
Title: Modeling fetal morphologic patterns through cardiotocography data: Decision tree-based approach
Category: General Sciences
Section: Research Article
Country: India
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Objective: The present research aims at decision tree (DT) modeling of fetal morphologic patterns by exploring cardiotocography (CTG). CTG consists of fetal heart rate and topographic measurements and is used for the verification of fetal health. Materials and Methods: In the present study, we have carried out DT modeling for CTGs data classification based on fetal morphologic patterns. Decision tree model is the most commonly used data mining technique for classification and prediction. The dataset employed in the present study comprises ten classes of morphologic patterns with a sample size of 2126 records. The optimum decision tree model is derived by tuning parameters such as min split, min bucket, max depth, and complexity. This model entails recursive partitioning approach implemented in the “rpart” package of R. The performance of the model is evaluated in terms of mean square error estimate of error rate. Results: Thus, derived decision tree model leads to values for tuning parameters such as min split, min bucket, max depth, and complexity are 20, 7, 30, and 0.01, respectively. The 1488 observations from the inputted dataset are considered for the construction of the tree. Root node error is 0.7211. Thus, derived DT model efficiently classifies validation data with very less error. Conclusion: The result suggests that the DT modeling has the potential to exhibit as the best tool for modeling of CTG data.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-P'Col-00001923
Title: Phytochemical screening and in vitro antioxidant activities of ethanolic gel extract of Aloe adigratana Reynolds
Category: Pharmacology
Section: Research Article
Country: India
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Objective: Aloe adigratana Reynolds is an herb that belongs to the Xanthorrhoeaceae family. It is native species to Tigray region in Northern Ethiopia and locally known as ere, it is called the healing plant because of its wound and burn healing properties. The present study was carried out to perform the phytochemical screening with different organic solvents and evaluate the in vitro antioxidant activities of ethanolic extract of A. adigratana Reynolds gel. Methods: The present study was to assess the qualitative phytochemical analysis and in vitro antioxidants potential of ethanolic extract of A. adigratana Reynolds gel by 1,1-diphenyl-2-picrylhydrazyl, reducing power assay, hydroxyl radical, nitric oxide, and superoxide radical scavenging activities using standard methods. Results: Qualitative phytochemical screening revealed that ethanolic extract of A. adigratana Reynolds gel contained a maximum number of secondary metabolites such as flavonoids, tannins and phenolic compounds, and terpenoid then other solvent extracts; further, the in vitro antioxidant activity of A. adigratana Reynolds ethanolic gel extract showed significant superoxide radical and nitric oxide scavenging activity with 76.67% and 65.39% inhibition with half maximal inhibitory concentration = 36.94 µg/ml and 62.35 µg/ml, respectively. Conclusion: It can be concluded that ethanolic extract of A. adigratana Reynolds gel had significant antioxidant properties, due to the presence of polyphenolic compounds, and could serve as a potential source of natural antioxidants, for the development of therapeutic antioxidant drugs.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-Pe-00001924
Title: Incidence of golden proportion among a target South Indian population
Category: Periodontics
Section: Research Article
Country: India
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Background: There are certain esthetic algorithms in nature like the Fibonacci sequence and the closely related golden proportion. In dentistry, the golden proportion has been suggested as one possible mathematical approach to the development of ideal size and shape relationships for maxillary teeth. Although several studies are available regarding the measurement of golden proportion in Caucasian populations, we do not have enough data regarding golden proportion measurements in the South Indian population. This survey is a small step toward addressing this gap in the literature. Aim: This study aims to survey the incidence of golden proportion between the widths of the maxillary anterior teeth among a target South Indian population. Materials and Methods: The study included 100 patients, 50 male and 50 female patients of age group of 20–30 years. Digital camera was used to measure the widths of the maxillary anterior teeth: Central incisor, lateral incisor, and canine. Standard frontal image of subject’s smile was taken using Canon 550 AF Lens 18–55mm. The image was downloaded to a personal computer and measurements of maxillary and mandibular anteriors were measured using a software called image measurement. Results: In the present study male South Indian population, the central incisor is smaller when compared to the ideal golden proportion, whereas canine is larger. The ratio of 1.2 was more commonly observed in 89% of individuals than 1.618 and 1.3 only in 11% of samples. Conclusion: The proportion between the maxillary central incisor, lateral incisor, and canine is consistent in both males and females. The central incisor is slightly smaller and canine is larger than the ideal golden proportion.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-Pe-00001925
Title: Role of essential plant oils in the treatment of periodontal and oral diseases
Category: Periodontics
Section: Review Article
Country: India
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Essential oils (EO) have been used as an adjuvant modality of treatment in the management of several orofacial diseases. They are primarily herbal extracts composed of complex organic hydrocarbons. The EO are extracted through a strenuous process of filtration and distillation from the naturally available botanical sources. They exhibit various therapeutic properties including antibacterial, antifungal, and antiviral properties. They also possess anxiolytic and antipsychotic properties. EO are relatively free of harmful side effects and allergic reactions. This review describes the potential applications of various EO in the management of periodontal and other oral diseases.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-HM-00001926
Title: Plant remedies for peptic ulcer – A review
Category: Herbal medicine
Section: Review Article
Country: India
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An ulcer is an erosion in the lining of the stomach or duodenum. An ulcer in the stomach is called a gastric ulcer and that ulcer in the duodenum is called a duodenal ulcer. Together, ulcers of the stomach and duodenum are referred to as peptic ulcers. Peptic ulcer disease, encompassing gastric and duodenal ulcers, is the most prevalent gastrointestinal disorder. Generation of free radicals, decrease in mucosal defensive factor or increase in mucosal injurious factors causes peptic ulcer. Hence, through this review, we explore the possibility about some plants and their constituents that may be used in treatment or prevention of peptic ulcer. Peptic ulcer, usually occurs due to poor recreation, little rest, and lack of physical exercise, due to the consumption of chocolates, candies, coffee, cigarettes, alcohol, stress causing segregation of acid in the stomach, due to the consumption of antacid medications, and due to side effects that can cause constipation such as baking soda, white soda, alkalizing products, magnesium, and aluminum hydroxide. The present study was aimed to elaborate on various herbs such as Aloe vera, Azadirachta indica, Carica papaya Linn., Allium sativum, and Mangifera indica which are used in treating peptic ulcer in various parts of the world.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-Pe-00001927
Title: Vertical root fracture
Category: Periodontics
Section: Review Article
Country: India
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Prompt diagnosis of vertical fracture in teeth could cause difficulties to practitioner but with various specific clinical and radiographic signs that are present during diagnosis could alert clinicians to the existence of such fractures. Hence, this review describes diagnosis of a vertical root fractures with its clinical and radiographic signs and presents treatment strategies for the same.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-HM-00001928
Title: Antioxidants and cancer prevention - A review
Category: Herbal medicine
Section: Review Article
Country: India
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Antioxidant therapy and free radicals have attracted in a lot of consideration in recent years. Antioxidants are compounds that destroy the free radicals in the body, thereby preventing harmful oxidation-reduction reactions. Antioxidants are important for maintaining good health. The best sources of antioxidants are fruits and vegetables, which provide a variety of antioxidants such as Vitamins A, C, E, and carotenoids. Data that are presently available are compatible with the notion that these vitamins act as chemopreventives against some important cancers such as carotenoids for lung cancer, ascorbic acid for salivary gland cancer, and tocopherols for head-and-neck cancers. Hence, a greater consumption of fruits and vegetables should be encouraged as they are the natural sources of these chemopreventive antioxidants along with other protective factors packaged by nature

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-P'Col-00001929
Title: Oral manifestation and management of systemic lupus erythematosus - A short review
Category: Pharmacology
Section: Review Article
Country: India
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Systemic lupus erythematosus (SLE) is a disease of unknown origin that can affect organs and cause severe damage. Lupus is diagnosed through biopsies and laboratory examinations; however, certain clinical characteristics and the presence of lesions can help with early diagnosis and improve the disease prognosis. SLE patients generally receive immune suppressants that may cause systemic implications - such as suture dehiscence, increased risk of infection, and delayedhealing - that deserve specific attention during dental treatment. This review presents studies done on SLE patient with oral manifestations: Ulcerative lesions in the mouth and brief about the treatment modality.

Journal: Journal of Pharmacy Research , Volume: 12, Issue: 1.
Article Id: JPRS-PC-00001941
Title: Synthesis and antitumor evaluation of indole-substituted indole-fused keto hydrazide–hydrazones
Category: Pharmaceutical Chemistry
Section: Research Article
Country: India
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Aim: A new type of indole and substituted indole-linked keto hydrazide–hydrazones were designed, synthesized, and evaluated for their cytotoxicity against eight human cancer cell lines HeLa, A549, MCF-7, K562, HEK293, HT29, SF295, and HL60. Materials and Methods: The antitumor activity of the compounds was determined using MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide) reduction assay. Results and Discussion: The compound 10 exhibited potent antitumor activity on four cancer cell lines MCF-7, A549, K562, and HL60 with 50% inhibitory concentration (IC50) value of 8.81 μM, 14.11 μM, 14.75 μM, and 15.631 μM, whereas compound 13 shows on five cancer cell lines A549, MCF-7, K562, SF295, and HL60 with IC50 value of 16.319 μM, 9.44 μM, 18.38 μM, 13.513 μM, and 19.31 μM than the standard drug cisplatin, respectively. Conclusion: The compounds 10 and 13 may be act as potent antitumor agents in cancer chemotherapy.