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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).
Scopus Indexed (link http://www.scimagojr.com/journalsearch.php?q=21100325431&tip=sid&clean=0) 

Journal Metrics for this Journal of Pharmacy Research (Source ID: 21100325431): 2015(SNIP) Source Normalized Impact Per Paper : 0.575; SCImago Journal Rank (SJR):0.787; Impact Per Publication : 0.789 CiteScore 2016: 0.93(Top level : Life Science)

Year SJR Cites per document Year Value
2014 0.607 Cites / Doc. (4 years) 2014 0.607
2015 0.787 Cites / Doc. (4 years) 2015 0.789
2016 0.926 Cites / Doc. (4 years) 2016 0.926
    Cites / Doc. (3 years) 2014 0.607
    Cites / Doc. (3 years) 2015 0.789
    Cites / Doc. (2 years) 2014 0.607
    Cites / Doc. (2 years) 2015 0.789
2016   Cites / Doc. (4 years) 2016 0.926
Cites Year Value
External Cites per document 2014 0.607
External Cites per document 2015 0.789
External Cites per document 2016 0.926
Cites per document 2014 0.607
Cites per document 2015 0.789
Cites per document 2016 0.926

Manuscripts Published

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-PA-00001349
Title: Investigation of Hepatoprotective activity of Aerial Parts of Canna indica L. on carbon tetrachloride treated rats
Category: Pharmaceutical Analysis
Section: Research Article
Country: India
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The hepatoprotective activity of methanol extract of aerial parts of Canna indica L. plant was evaluated against carbon tetrachloride induced hepatotoxicity. Extract at doses (100 and 200mg/kg) restored the levels of all serum parameters like SGPT, SGOT, TB which were elevated in CCl4 administrated rats. A 10% liver homogenate was used for estimation of catalase, GSH content, LPO level for in vivo antioxidant status of liver. All LPO, Reduced GSH, Catalase levels were observed normal in extract treated rats. Histopathology demonstrated profound necrosis, lymphocytic infiltration was observed in hepatic architecture of carbon tetrachloride rats which were found to obtain near normalcy in extract plus carbon tetrachloride administrated rats. This clearly suggests that methanol extract of aerial parts of Canna indica L. has liver protective effect against carbon tetrachloride induced hepatotoxicity.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-PCS-0000508
Title: Gastroretentive Drug Delivery System: Current Approaches
Category: Pharmaceutics
Section: Review Article
Country: India
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Oral controlled release delivery systems are programmed to deliver the drug in predictable time frame that will increase the efficacy and minimize the adverse effects and increase the bioavailability of drugs. It is most widely utilized route of administration among all the routes that have been explored for systemic delivery of drugs via pharmaceutical products of different dosage form. Oral route is considered most natural, uncomplicated, convenient and safe due to its ease of administration, patient acceptance, and cost-effective manufacturing process. In order to overcome the drawbacks of conventional drug delivery systems, several technical advancements have led to the development of controlled drug delivery system that could revolutionize method of medication and provide a number of therapeutic benefits. One of the most widely gastro retentive drug delivery system. The present paper highlights the current approaches and another aspects of the GRDS.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-MB-0000775
Title: Antioxidant and antibacterial activity of lichen extracts, honey and their combination
Category: Microbiology
Section: Research Article
Country: India
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The present study was carried to evaluate antioxidant and antibacterial activity of two macrolichens Parmotrema pseudotinctorum (des. Abb.) Hale and Ramalina hossei H. Magn & G. Awasthi individually and in combination with honey. The powdered lichen materials were extracted with methanol solvent. Antioxidant activity was assessed using DPPH free radical scavenging assay and antibacterial activity was determined by performing Agar well diffusion method. Antioxidant activity of combination of honey and lichen extracts was not as effective as scavenging potential of individual lichen extracts. Extracts of P. pseudotinctorum and R. hossei exhibited marked antibacterial activity individually than in combination with honey. Among all, honey showed less antioxidant and antibacterial activity. Thus, combination of lichen extracts and honey was not found to exert any synergistic action.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-P'Col-0000650
Title: In vivo anticonvulsant activity of Aegle marmelos Corr. Against pentylenetetrazole and electroconvulsive seizure in mice.
Category: Pharmacology
Section: Research Article
Country: India
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Aegle marmelos Corr. (Rutaceae) which has been widely used as an antiepileptic remedy in Indian traditional medicine. Different parts like leaves and ripe fruits have been used in the treatment of diarrhoeas, dysenteries, epilepsy and diabetes mellitus. We have taken aqueous extract isolated from the fruits of A. marmelos and studied their toxic effects. Acute, subacute and LD50 values were determined in experimental rats. Phytochemical investigations revealed the presence of flavonoids, tannins and steroids. The anticonvulsant activity of aqueous extract of the fruits of A. marmelos was examined against experimental seizures induced by Pentylenetetrazole and Electroshock in mice at a dose level of 200 and 300 mg/kg. The aqueous extract of the fruits of A. marmelos protected mice against tonic convulsions induced by maximal electroshock and especially by pentylenetetrazole in mice. Data obtained from convulsion tests were expressed as mean ± SEM and were analyzed by one-way analysis of varience (ANOVA) followed by Dunnette’s multiple comparison test.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-PA-0000649
Title: RP-HPLC Estimation of Entacapone in Bulk and Dosage Form
Category: Pharmaceutical Analysis
Section: Research Article
Country: India
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A simple, efficient and reproducible method for the determination of entacapone in tablets has been developed using reverse phase high performance liquid chromatographic method. The elution was done using a mobile phase consisting of acetonitrile and methanol (50:50 v/v) pH adjusted to 2.75 with ortho-phosphoric acid on inertsil C18, 4.6 × 250 mm analytical column with flow rate of 1 ml/min with detection at 315 nm. An external standard calibration method was employed for quantitation. The elution time was 3.15 ± 0.02 min. The linearity was 2-12 µg/ml for entacapone.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-PHDRS-0000647
Title: Salvadora Persica L (Tooth Brush Tree): A Review
Category: Pharmacognosy and Herbal Drugs related study
Section: Review Article
Country: India
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Salvadora persica L. also known as tooth brush tree belonging to the Salvadoraceae family. Plant has been reported to have anti-microbial, anti-plaque, aphrodisiac, alexiteric, analgesic, anti-inflammatory, anti-pyretic, astringent, diuretic and bitter stomachic activities. It has great medicinal use in the treatment of nose troubles, piles, scabies, leucoderma, scurvy, gonorrhea, boils and toothache. It contains important phyto-constituents such as vitamin-c, salvadorine, salvadourea, alkaloids, trimethylamine, cyanogenic glycosides, tannins, saponins and salts mostly as chlorides.In view of the immense medicinal importance of the plant this review is an effort to compile all the information reported on its phytochemical, biological and pharmacological activities. The present review is an attempt to generate interest among the people regarding its immense potential in preventing and treating several common diseases like tooth decay, plaque etc.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-PCS-0000645
Title: Chemical Penetration Enhancement: A Review
Category: Pharmaceutics
Section: Research Article
Country: India
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Transdermal drug delivery system is now a promising drug delivery system. Modern transdermal drug delivery systems are products of basic pharmaceutical research that took place during the last third of the 20th century. The literature on transdermal delivery of drugs has been revised. The transdermal drug delivery system has potential advantages of avoiding hepatic first pass metabolism, maintaining constant blood levels for longer period of time, decrease side effects, decrease gastrointestinal effect that occur due to local contact with gastric mucosa and improved compliance. The success of dermatological or transdermal drug delivery systems depends on the ability of the drug to penetrate into and/or permeate through skin in sufficient quantities to achieve desired therapeutic levels. In this article, the most recent chemical penetration enhancers on transdermal delivery systems is intended to summarize the progress in TDDS research and development (R&D).

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-ND-0000644
Title: An Overview On Certain Anticancer Natural Products
Category: Natural Drugs
Section: Review Article
Country: India
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Cancer is the second leading cause of death in developed and developing countries. It may be caused due to incorrect diet, genetic predisposition or environmental factors. At least 35% of all cancers worldwide are caused by incorrect diet. The plant kingdom has a great place in the treatment of diseases with no ill effect. Numerous plant products are now used for the remedy of cancer. According to WHO estimates, more than 80% people in developing countries depend on traditional medicine for their primary health needs. Consumption of large amount of vegetables and fruits can prevent the development of cancer. Several natural products are available as chemoprotective agents against various types of cancer. These chemoprotective agents are present in fruits, vegetables, plant extracts, herbs, microbes and marine organisms. A host of natural product constituents could be responsible for the protective effect against cancer. Although the mechanism of the protective effect is unclear, nevertheless, the consumption of natural products lowers the incidence of cancer. A major group of these products are the powerful antioxidants, others are phenolic in nature and the remainder includes reactive groups. This article emphasizes many anticancer natural products obtained from plant, microbe and marine sources, which possess potent anticancer activity.  

Journal: Journal of Pharmacy Research , Volume: 2, Issue: 12.
Article Id: JPRS-PCS-0000648
Title: Formulation, Optimization and Evaluation of Mometasone Furoate Gel
Category: Pharmaceutics
Section: Research Article
Country: India
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The objective of this work was to develop the semi-solid topical gel formulations of mometasone furoate and study in vitro skin penetration through rat skin. The concentration of carbopol 940, ethanol and propylene glycol in gel formulation was optimized by Box-Behnken statistical screening design. The concentration of carbopol 940 (X1), concentration of ethanol (X2) and concentration of propylene glycol (X3) were selected as independent variables. The flux (j), total amount released at 8 hours (Q8) and enhancement Ratio (ER) were selected as dependent variables. All gel formulations showed good results for different parameters like drug content, pH, viscosity, and spredibility. A marked effect of independent variables (concentration of carbopol 940, ethanol and Propylene Glycol) on mometasone furoate permeation was observed when it was incorporated gel formulations. The values of J, ER and Q8 were strongly dependent on the independent variables.