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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).
Scopus Indexed (link http://www.scimagojr.com/journalsearch.php?q=21100325431&tip=sid&clean=0) 

Journal Metrics for this Journal of Pharmacy Research (Source ID: 21100325431): 2015(SNIP) Source Normalized Impact Per Paper : 0.575; SCImago Journal Rank (SJR):0.787; Impact Per Publication : 0.789 CiteScore 2016: 0.93(Top level : Life Science)

Year SJR Cites per document Year Value
2014 0.607 Cites / Doc. (4 years) 2014 0.607
2015 0.787 Cites / Doc. (4 years) 2015 0.789
2016 0.926 Cites / Doc. (4 years) 2016 0.926
    Cites / Doc. (3 years) 2014 0.607
    Cites / Doc. (3 years) 2015 0.789
    Cites / Doc. (2 years) 2014 0.607
    Cites / Doc. (2 years) 2015 0.789
2016   Cites / Doc. (4 years) 2016 0.926
Cites Year Value
External Cites per document 2014 0.607
External Cites per document 2015 0.789
External Cites per document 2016 0.926
Cites per document 2014 0.607
Cites per document 2015 0.789
Cites per document 2016 0.926

Manuscripts Published

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PC-0000625
Title: Spectrophotometric method for the estimation of domperidone in bulk and pharmaceutical formulations
Category: Pharmaceutical Chemistry
Section: Research Article
Country: India
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A simple and sensitive spectrophotometric method has been developed for the estimation of domperidone in bulk and pharmaceutical formulations. The estimation of domperidone was carried out on a UV/VIS spectrophotometer (Analytical technologies) using 1 cm quartz cell. Domperidone obeyed Beer’s law in a concentration range of 10 to 150µg/ml exhibiting maximum absorption at 284 nm. This method is extended to pharmaceutical additive and diluent. The results have been validated statistically and recovery studies confirmed the accuracy of proposed method.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PHDRS-0000630
Title: Total Phenolic content and antioxidant activity of aqueous and methanol extracts of Dioscorea alata tuber
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
Country: India
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Antioxidant activity of aqueous extract (DAAE) and methanol extract (DAME) of Dioscorea alata tuber were evaluated using DPPH radical scavenging and reducing power assay. DAME contained significantly higher (p < 0.05) phenolics compared to DAAE and showed significantly higher (p < 0.05) radical scavenging activity (84%) than DAAE (12.6%). The radical scavenging activity of DAME was comparable with that of BHT (85%) at 100 µg/ml concentration. DAME also showed higher reducing power than DAAE. A significant (p <0.01) correlation was observed between the phenolic content and the radical scavenging activity of the extracts indicating the contribution of phenolic compounds for the observed antioxidant effect.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PHDRS-0000627
Title: Preliminary phytochemical and antibacterial screening of crude extract of Tridax procumbens. L
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
Country: India
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Preliminary phytochemical and antibacterial investigations were carried out of the crude extract obtained from the entire plant of Tridax procumbens Linn. The presence of phenols, tannins, saponins, flavanoids, aminoacids and reducing sugars was indicated by the tests conducted. The effect of methanol extract was tested on Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeroginosa and Salmonella typhi  . The minimum inhibitory concentration of the crude extracts was determined for various organisms.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PA-0000626
Title: A sensitive and selective RP-HPLC method for the determination of lamivudine and stavudine in tablets
Category: Pharmaceutical Analysis
Section: Research Article
Country: India
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A simple, fast, precise and accurate reverse phase high performance liquid chromatographic method developed for the simultaneous determination and validation of lamivudine (3TC) and stavudine (d4T)  in tablets. A sunfire C18, 250 × 4.6 mm, 5 mm particle size column in isocratic mode was used with mobile phase comprising of methanol: 0.1 % w/v of ammonium acetate, adjusted to pH 3.8 with glacial acetic acid in the ratio of 15:85, v/v. The flow rate was set at 1.2 ml per minute with UV detection at 266 nm. The retention time of 3TC, d4T was found 5.6 and 8.9 minute respectively. Linearity for lamivudine and stavudine were found in the range of 75-225mg/ml and 20-60mg/ml respectively. Percentage recoveries were obtained in the range of 98.97 % to 99.71 % for lamivudine and 99.22 % to 99.59 % for stavudine. The proposed method is precise, accurate, selective, reproducible, and rapid for the simultaneous estimation of lamivudine and stavudine in tablet dosage forms.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-HM-0000624
Title: Formulation and evaluation of Aloe vera gels
Category: Herbal medicine
Section: Research Article
Country: India
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The Aloe vera plant is popular and well known for its medicinal uses across the world. The most popularly known species of Aloe vera which is grown world wide is Aloe barbadensis Miller. Gel derived from Aloe vera is mucilaginous exudate obtained from centre (parenchyma) of the plant leaf. The Aloe vera extract is used for many years as a natural herbal and safe remedy in various skin problems. Several marketed preparations in the form of gels and lotions containing Aloe vera are available. The present study is an attempt to formulate gel formulations of Aloe vera using synthetic polymers like Carbopol 934NF, HPMC and PVP36000. These formulations were prepared in concentrations of 1, 2 and 3% of respective polymers. These gels were further subjected to evaluation of properties like colour, clarity, pH, consistency, and viscosity measurements. Comparison of the results was done in an attempt to find an optimized Aloe vera gel formulation.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PCS-0000623
Title: Formulation Optimization and Evaluation of Mometasone Furoate Cream
Category: Pharmaceutics
Section: Research Article
Country: India
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The aim of the present investigation was to develop topical cream formulations of mometasone furoate and study its permeation through rat skin. The surfactant concentration was optimized using 32 full factorial designs. The concentration of Tween 80 (X1) and concentration of Span 80 (X2) were selected as independent variables. The flux (j), cumulative amount released at 8 hours (Q8) and Enhancement ratio (ER) were selected as dependent variables. All cream formulations showed good results for different parameters like drug content, pH, viscosity, and spredibility. The penetration enhancing effect of menthol (0–10% w/w) on the percutaneous flux of mometasone furoate through the excised rat epidermis was also investigated. A marked effect of surfactants (Tween 80 Span 80) concentration on mometasone furoate permeation was observed when it was incorporated cream formulations. The values of J, ER and Q8 were strongly dependent on the independent variables. The percutaneous flux and enhancement ratio of mometasone furoate across rat epidermis was significantly increased by the addition of menthol to the cream formulations.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PCS-0000622
Title: Development and validation of new RP-HPLC method with UV detection for the determination of rifampicin in plasma
Category: Pharmaceutics
Section: Research Article
Country: India
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To standardize a high-performance liquid chromatography (HPLC) method for the determination of rifampicin in plasma by external standard method.Material and Methods: A simple, specific and sensitive HPLC method was developed for the determination of rifampicin in plasma. Separation was achieved by reverse phase chromatography on a C18 column with a mobile phase composition of phosphate buffer pH 7.4: methanol (75:25 v/v) at 475 nm.Results: The retention time of rifampicin was 2.54 minutes. The assay was linear from 0.05 to 20.0 mgm /mL for plasma. Both intra-day and inter-day accuracy and precision data showed good reproducibility. Recoveries (extraction efficiency) for drug were greater than 90% in plasma .The plasma method was precise (total coefficient of variation ranged from 1.46 to 6.71%) for the analytes.Conclusion: The HPLC method described is sensitive, selective and linear for the wide range of concentrations for rifampicin in plasma. Thus, the method developed is well suited for the pharmacokinetic studies.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PCS-0000620
Title: Development and characterization extended release gastroretentive drug delivery
Category: Pharmaceutics
Section: Research Article
Country: India
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The purpose of the experimental study was to design an extended release floating tablets of ranitidine hydrochloride and investigate the effect of formulation variables on drug release profile and floating property. Ranitidine hydrochloride (RHCl) was used as a model drug because of its short biological half life and site of release at stomach. Tablets were formulated using different concentration hydroxypropyl methyl cellulose K4M, carbopol 934 and sodium carboxymethyl cellulose .where Sodium bicarbonate and Citric acid used as a gas generating agent. The floating behavior and in-vitro dissolution studies are carried out in a USP type II apparatus in 0.1(N) Hcl. It was observed that all the prepared formulation shows good floating capabilities up to 11 to 18 hours and slow steady release profile up to 12 hours. The dissolution profiles were subjected various kinetic release equations and found that drug release from different polymeric matrix follows diffusion controlled release.

Journal: Journal of Pharmacy Research , Volume: 2, Issue: October
Article Id: JPRS-PP-0000629
Title: Isolation and Characterization of New Lanosteriod from Ethanolic Extract of Eclipta alba Linn.
Category: Pharmacognosy and Phytochemistry,
Section: Research Article
Country: India
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In present investigations, whole plant of Eclipta alba was extracted in soxhlet apparatus using 95% ethanol as solvent. The dried ethanolic extract of Eclipta alba Linn.  was further eluted with mobile phase of petroleum ether: chloroform (1:6) using silica gel column to elute compound 1 i.e. terpenoids (Identified by thin layer chromatography). The compound 1 was subjected to spectroscopic studies (IR, PNMR, 13CNMR and Mass spectroscopy) for structure elucidation. On the basis of the spectral data analysis and chemical reactions, the structure of compound 1 has been established as lanost – 5, 24 – dien – 3 β– ol – 18, 21 – olide -3 β- yl tetradecanoate (a lanosteroid).